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Application of artificial intelligence and machine learning for COVID-19 drug discovery and vaccine design.
Lv, Hao; Shi, Lei; Berkenpas, Joshua William; Dao, Fu-Ying; Zulfiqar, Hasan; Ding, Hui; Zhang, Yang; Yang, Liming; Cao, Renzhi.
  • Lv H; Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China.
  • Shi L; Department of Spine Surgery, Changzheng Hospital, Naval Medical University, Shanghai 200433, China.
  • Berkenpas JW; Department of Computer Science, Pacific Lutheran University, Tacoma 98447, USA.
  • Dao FY; Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China.
  • Zulfiqar H; Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China.
  • Ding H; Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China.
  • Zhang Y; Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
  • Yang L; Department of Pathophysiology, Harbin Medical University-Daqing, Daqing, 163319, China.
  • Cao R; Department of Computer Science, Pacific Lutheran University, Tacoma 98447, USA.
Brief Bioinform ; 22(6)2021 11 05.
Article in English | MEDLINE | ID: covidwho-1364739
ABSTRACT
The global pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, has led to a dramatic loss of human life worldwide. Despite many efforts, the development of effective drugs and vaccines for this novel virus will take considerable time. Artificial intelligence (AI) and machine learning (ML) offer promising solutions that could accelerate the discovery and optimization of new antivirals. Motivated by this, in this paper, we present an extensive survey on the application of AI and ML for combating COVID-19 based on the rapidly emerging literature. Particularly, we point out the challenges and future directions associated with state-of-the-art solutions to effectively control the COVID-19 pandemic. We hope that this review provides researchers with new insights into the ways AI and ML fight and have fought the COVID-19 outbreak.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Drug Discovery / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Drug Treatment Type of study: Observational study Topics: Vaccines Limits: Humans Language: English Journal subject: Biology / Medical Informatics Year: 2021 Document Type: Article Affiliation country: Bib

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Drug Discovery / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Drug Treatment Type of study: Observational study Topics: Vaccines Limits: Humans Language: English Journal subject: Biology / Medical Informatics Year: 2021 Document Type: Article Affiliation country: Bib