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Prevalence and determinants of symptomatic COVID-19 infection among children and adolescents in Qatar: a cross-sectional analysis of 11 445 individuals.
Musa, Omran A H; Chivese, Tawanda; Bansal, Devendra; Abdulmajeed, Jazeel; Ameen, Osman; Islam, Nazmul; Xu, Chang; Sallam, Mohamed A; Albayat, Soha S; Khogali, Hayat S; Ahmed, Shazia N N; Himatt, Sayed M; Nour, Mohamed; Elberdiny, Aiman A; Musa, Abdallah; Furuya-Kanamori, Luis; Al-Romaihi, Hamad E; Doi, Suhail A R; Al-Thani, Mohammed H J; Abu Baker Abd Farag, Elmoubashar.
  • Musa OAH; Department of Population Medicine, College of Medicine, Qatar University, Doha, Qatar.
  • Chivese T; Department of Population Medicine, College of Medicine, Qatar University, Doha, Qatar.
  • Bansal D; Department of Public Health, Ministry of Public Health, Doha, Qatar.
  • Abdulmajeed J; Department of Strategy Planning & HI - Business & Health Intelligence, Primary Health Care Corporation, Doha, Qatar.
  • Ameen O; Department of Clinical Science, College of Medicine, Qatar University, Doha, Qatar.
  • Islam N; Department of Public Health, College of Health Sciences, Qatar University, Doha, Qatar.
  • Xu C; Department of Population Medicine, College of Medicine, Qatar University, Doha, Qatar.
  • Sallam MA; Department of Public Health, Ministry of Public Health, Doha, Qatar.
  • Albayat SS; Department of Public Health, Ministry of Public Health, Doha, Qatar.
  • Khogali HS; Department of Public Health, Ministry of Public Health, Doha, Qatar.
  • Ahmed SNN; Department of Public Health, Ministry of Public Health, Doha, Qatar.
  • Himatt SM; Department of Public Health, Ministry of Public Health, Doha, Qatar.
  • Nour M; Department of Public Health, Ministry of Public Health, Doha, Qatar.
  • Elberdiny AA; Department of Public Health, Ministry of Public Health, Doha, Qatar.
  • Musa A; Department of Basic Medical Science, College of Medicine, Qatar University, Doha, Qatar.
  • Furuya-Kanamori L; Faculty of Medicine, QU Centre for Clinical Research, The University of Queensland, Herston, Australia.
  • Al-Romaihi HE; Department of Public Health, Ministry of Public Health, Doha, Qatar.
  • Doi SAR; Department of Population Medicine, College of Medicine, Qatar University, Doha, Qatar.
  • Al-Thani MHJ; Department of Public Health, Ministry of Public Health, Doha, Qatar.
  • Abu Baker Abd Farag E; Department of Public Health, Ministry of Public Health, Doha, Qatar.
Epidemiol Infect ; 149: e193, 2021 07 02.
Article in English | MEDLINE | ID: covidwho-1366777
ABSTRACT
There is a paucity of evidence about the prevalence and risk factors for symptomatic infection among children. This study aimed to describe the prevalence of symptomatic coronavirus disease 2019 (COVID-19) and its risk factors in children and adolescents aged 0-18 years in Qatar. We conducted a cross-sectional study of all children aged 0-18 years diagnosed with COVID-19 using polymerase chain reaction in Qatar during the period 1st March to 31st July 2020. A generalised linear model with a binomial family and identity link was used to assess the association between selected factors and the prevalence of symptomatic infection. A total of 11 445 children with a median age of 8 years (interquartile range (IQR) 3-13 years) were included in this study. The prevalence of symptomatic COVID-19 was 36.6% (95% confidence interval (CI) 35.7-37.5), and it was similar between children aged <5 years (37.8%), 5-9 years (34.3%) and 10 + years (37.3%). The most frequently reported symptoms among the symptomatic group were fever (73.5%), cough (34.8%), headache (23.2%) and sore throat (23.2%). Fever (82.8%) was more common in symptomatic children aged <5 years, while cough (38.7%) was more prevalent in those aged 10 years or older, compared to other age groups. Variables associated with an increased risk of symptomatic infection were; contact with confirmed cases (RD 0.21; 95% CI 0.20-0.23; P = 0.001), having visited a health care facility (RD 0.54; 95% CI 0.45-0.62; P = 0.001), and children aged under 5 years (RD 0.05; 95% CI 0.02-0.07; P = 0.001) or aged 10 years or older (RD 0.04; 95% CI 0.02-0.06; P = 0.001). A third of the children with COVID-19 were symptomatic with a higher proportion of fever in very young children and a higher proportion of cough in those between 10 and 18 years of age.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pharyngitis / Cough / Fever / COVID-19 / Headache Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Infant, Newborn Country/Region as subject: Asia Language: English Journal: Epidemiol Infect Journal subject: Communicable Diseases / Epidemiology Year: 2021 Document Type: Article Affiliation country: S0950268821001515

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pharyngitis / Cough / Fever / COVID-19 / Headache Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Infant, Newborn Country/Region as subject: Asia Language: English Journal: Epidemiol Infect Journal subject: Communicable Diseases / Epidemiology Year: 2021 Document Type: Article Affiliation country: S0950268821001515