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The Impact of COVID-19 in Gastroenterology and Hepatology.
Ramkissoon, Resham; Wang, Xiao Jing.
  • Ramkissoon R; Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN.
J Clin Gastroenterol ; 55(9): 757-765, 2021 10 01.
Article in English | MEDLINE | ID: covidwho-1367075
ABSTRACT
The 2019 coronavirus disease (COVID-19), an airborne infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in a global pandemic. SARS-CoV-2 relies on the angiotensin-converting enzyme 2 receptor for cellular entry and the abundance of this receptor in the gastrointestinal (GI) tract may help explain the GI manifestations, including dysgeusia, nausea, vomiting, diarrhea, and abdominal pain, present in over 40% of infected patients. GI tract involvement also raises the concern for oral-fecal transmission which is poorly understood. Outcome studies in COVID-19 patients with preexisting liver disease and inflammatory bowel disease show predominantly mild transaminase elevations and no increased risk from the use of biological agents in inflammatory bowel disease patients. High-dose corticosteroids, however, should be avoided. As endoscopic procedures are aerosol-generating, modifications to clinical practice is necessary to minimize the spread of COVID-19. We have reviewed current literature to describe the impact of COVID-19 in gastroenterology and hepatology as well as targets of future research.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Gastroenterology / Gastrointestinal Diseases / COVID-19 Limits: Humans Language: English Journal: J Clin Gastroenterol Year: 2021 Document Type: Article Affiliation country: Mcg.0000000000001600

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Gastroenterology / Gastrointestinal Diseases / COVID-19 Limits: Humans Language: English Journal: J Clin Gastroenterol Year: 2021 Document Type: Article Affiliation country: Mcg.0000000000001600