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Update on geographical variation and distribution of SARS-nCoV-2: A systematic review.
Prajapat, Manisha; Handa, Vrishbhanu; Sarma, Phulen; Prakash, Ajay; Kaur, Hardeep; Sharma, Saurabh; Bhattacharyya, Anusuya; Kumar, Subodh; Sharma, Amit Raj; Avti, Pramod; Medhi, Bikash.
  • Prajapat M; Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
  • Handa V; Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
  • Sarma P; Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
  • Prakash A; Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
  • Kaur H; Department of Paediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
  • Sharma S; Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
  • Bhattacharyya A; Department of Ophthalmology, Government Medical College and Hospital, Chandigarh, India.
  • Kumar S; Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
  • Sharma AR; Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
  • Avti P; Department of Biophysics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
  • Medhi B; Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Indian J Pharmacol ; 53(4): 310-316, 2021.
Article in English | MEDLINE | ID: covidwho-1367965
ABSTRACT
Knowledge of a new mutant strain of SARS-coronavirus (CoV-2) is enormously essential to identify a targeted drug and for the development of the vaccine. In this article, we systematically reviewed the different mutation strains (variant of concern [VOC] and variant of interest [VOI]) which were found in different countries such as the UK, Singapore, China, Germany, Vietnam, Western Africa, Dublin, Ireland, Brazil, Iran, Italy, France, America, and Philippines. We searched four literature databases (PubMed, EMBASE, NATURE, and Willey online library) with suitable keywords and the time filter was November 2019 to June 16, 2021. To understand the worldwide spread of variants of SARS-CoV-2, we included a total of 27 articles of case reports, clinical and observational studies in the systematic review. However, these variants mostly spread because of their ability to increase transmission, virulence, and escape immunity. So, in this paper is we found mutated strains of SARS-CoV-2 like VOCs that are found in different regions across the globe are ALPHA strain in the U.K, BETA strain in South Africa, GAMMA strain in Brazil, Gamma and Beta strains in European Countries, and some VOIs like Theta variant in the Philippines.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 / Mutation Type of study: Diagnostic study / Observational study / Prognostic study / Reviews / Systematic review/Meta Analysis Topics: Vaccines / Variants Limits: Humans Language: English Journal: Indian J Pharmacol Year: 2021 Document Type: Article Affiliation country: Ijp.ijp_483_21

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 / Mutation Type of study: Diagnostic study / Observational study / Prognostic study / Reviews / Systematic review/Meta Analysis Topics: Vaccines / Variants Limits: Humans Language: English Journal: Indian J Pharmacol Year: 2021 Document Type: Article Affiliation country: Ijp.ijp_483_21