The association of metabolic syndrome and COVID-19 deterioration.
Nutr Metab Cardiovasc Dis
; 31(11): 3236-3242, 2021 10 28.
Article
in English
| MEDLINE | ID: covidwho-1370657
ABSTRACT
BACKGROUND AND AIMS:
To evaluate the prevalence and prognostic value of metabolic syndrome (MetS) in patients admitted for coronavirus disease 2019 (COVID-19). METHODS ANDRESULTS:
In this monocentric cohort retrospective study, we consecutively included all adult patients admitted to COVID-19 units between April 9 and May 29, 2020 and between February 1 and March 26, 2021. MetS was defined when at least three of the following components were met android obesity, high HbA1c, hypertension, hypertriglyceridemia, and low HDL cholesterol. COVID-19 deterioration was defined as the need for nasal oxygen flow ≥6 L/min within 28 days after admission. We included 155 patients (55.5% men, mean age 61.7 years old, mean body mass index 29.8 kg/m2). Fifty-six patients (36.1%) had COVID-19 deterioration. MetS was present in 126 patients (81.3%) and was associated with COVID-19 deterioration (no-MetS vs MetS 13.7% and 41.2%, respectively, p < 0.01). Logistic regression taking into account MetS, age, gender, ethnicity, period of inclusion, and Charlson Index showed that COVID-19 deterioration was 5.3 times more likely in MetS patients (95% confidence interval 1.3-20.2) than no-MetS patients.CONCLUSIONS:
Over 81.3% of patients hospitalized in COVID-19 units had MetS. This syndrome appears to be an independent risk factor of COVID-19 deterioration.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Metabolic Syndrome
/
COVID-19
Type of study:
Cohort study
/
Experimental Studies
/
Observational study
/
Prognostic study
Topics:
Variants
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Europa
Language:
English
Journal:
Nutr Metab Cardiovasc Dis
Journal subject:
Vascular Diseases
/
Cardiology
/
Nutritional Sciences
/
Metabolism
Year:
2021
Document Type:
Article
Affiliation country:
J.numecd.2021.08.036
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