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Case Report: COVID-19-associated Rhinosinusitis Mucormycosis Caused by Rhizopus arrhizus: A Rare but Potentially Fatal Infection Occurring After Treatment with Corticosteroids.
Tabarsi, Payam; Khalili, Neda; Pourabdollah, Mihan; Sharifynia, Somayeh; Safavi Naeini, Ali; Ghorbani, Jahangir; Mohamadnia, Abdolreza; Abtahian, Zahra; Askari, Elham.
  • Tabarsi P; 1Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Khalili N; 2School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
  • Pourabdollah M; 3Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
  • Sharifynia S; 4Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Safavi Naeini A; 1Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Ghorbani J; 4Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Mohamadnia A; 4Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Abtahian Z; 4Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Askari E; 1Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Am J Trop Med Hyg ; 105(2): 449-453, 2021 Jul 08.
Article in English | MEDLINE | ID: covidwho-1371040
ABSTRACT
COVID-19 first emerged in Wuhan, China, in December 2019. Since that time, the frequency of bacterial and fungal coinfections has been continuously increasing. Although invasive pulmonary aspergillosis is being increasingly recognized in association with COVID-19, there is limited information regarding COVID-19-associated mucormycosis. We describe a 50-year-old woman with uncontrolled diabetes who received systemic corticosteroids and remdesevir during her admission for COVID-19. A few days after discharge, the patient was readmitted because of facial swelling and numbness, and a diagnosis of COVID-19-associated rhinosinusitis mucormycosis caused by Rhizopus arrhizus (formerly called Rhizopus oryzae) was confirmed with sequencing of the internal transcribed spacer region of the ribosomal DNA. This report aimed to address the importance of short-term follow-up for COVID-19 patients who have received systemic corticosteroids, particularly those with predisposing conditions, because early detection and prompt, aggressive treatment are essential for the management of invasive fungal infections.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Sinusitis / Rhinitis / Adrenal Cortex Hormones / Rhizopus oryzae / SARS-CoV-2 / COVID-19 Type of study: Case report / Cohort study / Diagnostic study / Prognostic study Topics: Long Covid Limits: Female / Humans / Middle aged Language: English Journal: Am J Trop Med Hyg Year: 2021 Document Type: Article Affiliation country: Ajtmh.21-0359

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Sinusitis / Rhinitis / Adrenal Cortex Hormones / Rhizopus oryzae / SARS-CoV-2 / COVID-19 Type of study: Case report / Cohort study / Diagnostic study / Prognostic study Topics: Long Covid Limits: Female / Humans / Middle aged Language: English Journal: Am J Trop Med Hyg Year: 2021 Document Type: Article Affiliation country: Ajtmh.21-0359