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Population-based assessment of risks for severe COVID-19 disease outcomes.
Zerbo, Ousseny; Lewis, Ned; Fireman, Bruce; Goddard, Kristin; Skarbinski, Jacek; Sejvar, James J; Azziz-Baumgartner, Eduardo; Klein, Nicola P.
  • Zerbo O; Vaccine Study Center, Kaiser Permanente Northern California, Oakland, California, USA.
  • Lewis N; Vaccine Study Center, Kaiser Permanente Northern California, Oakland, California, USA.
  • Fireman B; Vaccine Study Center, Kaiser Permanente Northern California, Oakland, California, USA.
  • Goddard K; Vaccine Study Center, Kaiser Permanente Northern California, Oakland, California, USA.
  • Skarbinski J; Department of Infectious Diseases, Kaiser Permanente Northern California, Oakland, California, USA.
  • Sejvar JJ; COVID-19 Response Team, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Azziz-Baumgartner E; COVID-19 Response Team, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
  • Klein NP; Vaccine Study Center, Kaiser Permanente Northern California, Oakland, California, USA.
Influenza Other Respir Viruses ; 16(1): 159-165, 2022 01.
Article in English | MEDLINE | ID: covidwho-1371828
ABSTRACT
Among approximately 4.6 million members of Kaiser Permanente Northern California, we examined associations of severe COVID-19 with demographic factors and comorbidities. As of July 23, 2021, 16 182 had been hospitalized, 2416 admitted to an ICU, and 1525 died due to COVID-19. Age was strongly associated with hospitalization, ICU admission, and death. Black persons and Hispanic ethnicity had higher risk of death compared with Whites. Among the comorbidities examined, Alzheimer's disease was associated with the highest risk for hospitalization (aHR 3.19, CI 2.88-3.52) and death (aHR 4.04, CI 3.32-4.91). Parkinson's disease had the second highest risk of death (aHR = 2.07, CI 1.50-2.87).
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: Influenza Other Respir Viruses Journal subject: Virology Year: 2022 Document Type: Article Affiliation country: Irv.12901

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: Influenza Other Respir Viruses Journal subject: Virology Year: 2022 Document Type: Article Affiliation country: Irv.12901