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Pan-drug resistant Providencia rettgeri contributing to a fatal case of COVID-19.
Mc Gann, Patrick; Geringer, Matthew R; Hall, Lindsey R; Lebreton, Francois; Markelz, Elizabeth; Kwak, Yoon I; Johnson, Sheila; Ong, Ana C; Powell, Aubrey; Tekle, Tsigereda; Bergman, Yehudit; Simner, Patricia J; Bennett, Jason W; Cybulski, Robert J; White, Brian K.
  • Mc Gann P; Multidrug-Resistant Organism Repository and Surveillance Network (MRSN), Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Geringer MR; Infectious Disease Service, Brooke Army Medical Center, San Antonio, Texas, USA.
  • Hall LR; Multidrug-Resistant Organism Repository and Surveillance Network (MRSN), Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Lebreton F; Multidrug-Resistant Organism Repository and Surveillance Network (MRSN), Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Markelz E; Infectious Disease Service, Brooke Army Medical Center, San Antonio, Texas, USA.
  • Kwak YI; Multidrug-Resistant Organism Repository and Surveillance Network (MRSN), Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Johnson S; Multidrug-Resistant Organism Repository and Surveillance Network (MRSN), Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Ong AC; Multidrug-Resistant Organism Repository and Surveillance Network (MRSN), Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Powell A; Department of Pathology and Area Laboratory Services, Brooke Army Medical Center, San Antonio, Texas, USA.
  • Tekle T; Division of Medical Microbiology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Bergman Y; Division of Medical Microbiology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Simner PJ; Division of Medical Microbiology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Bennett JW; Multidrug-Resistant Organism Repository and Surveillance Network (MRSN), Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
  • Cybulski RJ; Department of Pathology and Area Laboratory Services, Brooke Army Medical Center, San Antonio, Texas, USA.
  • White BK; Infectious Disease Service, Brooke Army Medical Center, San Antonio, Texas, USA.
J Med Microbiol ; 70(8)2021 Aug.
Article in English | MEDLINE | ID: covidwho-1376363
ABSTRACT
Following prolonged hospitalization that included broad-spectrum antibiotic exposure, a strain of Providencia rettgeri was cultured from the blood of a patient undergoing extracorporeal membrane oxygenation treatment for hypoxic respiratory failure due to COVID-19. The strain was resistant to all antimicrobials tested including the novel siderophore cephalosporin, cefiderocol. Whole genome sequencing detected ten antimicrobial resistance genes, including the metallo-ß-lactamase bla NDM-1, the extended-spectrum ß-lactamase bla PER-1, and the rare 16S methyltransferase rmtB2.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Providencia / Drug Resistance, Bacterial / Enterobacteriaceae Infections / Pneumonia, Ventilator-Associated / COVID-19 / Anti-Bacterial Agents Type of study: Case report / Prognostic study Topics: Long Covid Limits: Aged / Humans / Male Language: English Year: 2021 Document Type: Article Affiliation country: Jmm.0.001406

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Providencia / Drug Resistance, Bacterial / Enterobacteriaceae Infections / Pneumonia, Ventilator-Associated / COVID-19 / Anti-Bacterial Agents Type of study: Case report / Prognostic study Topics: Long Covid Limits: Aged / Humans / Male Language: English Year: 2021 Document Type: Article Affiliation country: Jmm.0.001406