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Functional data analysis characterizes the shapes of the first COVID-19 epidemic wave in Italy.
Boschi, Tobia; Di Iorio, Jacopo; Testa, Lorenzo; Cremona, Marzia A; Chiaromonte, Francesca.
  • Boschi T; Dept. of Statistics and Huck Institutes of the Life Sciences, Penn State University, University Park, PA, 16802, USA.
  • Di Iorio J; Institute of Economics and EMbeDS, Sant'Anna School of Advanced Studies, 56127, Pisa, Italy.
  • Testa L; Institute of Economics and EMbeDS, Sant'Anna School of Advanced Studies, 56127, Pisa, Italy.
  • Cremona MA; Dept. of Statistics and Huck Institutes of the Life Sciences, Penn State University, University Park, PA, 16802, USA. marzia.cremona@fsa.ulaval.ca.
  • Chiaromonte F; Dept. of Operations and Decision Systems, Université Laval, Quebec, G1V 0A6, Canada. marzia.cremona@fsa.ulaval.ca.
Sci Rep ; 11(1): 17054, 2021 08 30.
Article in English | MEDLINE | ID: covidwho-1379331
ABSTRACT
We investigate patterns of COVID-19 mortality across 20 Italian regions and their association with mobility, positivity, and socio-demographic, infrastructural and environmental covariates. Notwithstanding limitations in accuracy and resolution of the data available from public sources, we pinpoint significant trends exploiting information in curves and shapes with Functional Data Analysis techniques. These depict two starkly different epidemics; an "exponential" one unfolding in Lombardia and the worst hit areas of the north, and a milder, "flat(tened)" one in the rest of the country-including Veneto, where cases appeared concurrently with Lombardia but aggressive testing was implemented early on. We find that mobility and positivity can predict COVID-19 mortality, also when controlling for relevant covariates. Among the latter, primary care appears to mitigate mortality, and contacts in hospitals, schools and workplaces to aggravate it. The techniques we describe could capture additional and potentially sharper signals if applied to richer data.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Epidemics / COVID-19 Type of study: Observational study / Prognostic study Limits: Humans Country/Region as subject: Europa Language: English Journal: Sci Rep Year: 2021 Document Type: Article Affiliation country: S41598-021-95866-y

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Epidemics / COVID-19 Type of study: Observational study / Prognostic study Limits: Humans Country/Region as subject: Europa Language: English Journal: Sci Rep Year: 2021 Document Type: Article Affiliation country: S41598-021-95866-y