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Role of neutrophils in acute viral infection.
Ma, Yuan; Zhang, Yue; Zhu, Liuluan.
  • Ma Y; Institute of Infectious Diseases, Peking University Ditan Teaching Hospital, Beijing, China.
  • Zhang Y; Beijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
  • Zhu L; Institute of Infectious Diseases, Peking University Ditan Teaching Hospital, Beijing, China.
Immun Inflamm Dis ; 9(4): 1186-1196, 2021 12.
Article in English | MEDLINE | ID: covidwho-1384181
ABSTRACT
Neutrophils play multiple roles in acute viral infections. They restrict viral replication and diffusion through phagocytosis, degranulation, respiratory burst, secretion of cytokines, and the release of neutrophil extracellular traps, as well as, activate the adaptive immune response. However, the overactivation of neutrophils may cause tissue damage and lead to poor outcomes. Additionally, some characteristics and functions of neutrophils, such as cell number, lifespan, and antiviral capability, can be influenced while eliminating viruses. This review provides a general description of the protective and pathological roles of neutrophils in acute viral infection.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Virus Diseases / Extracellular Traps Limits: Humans Language: English Journal: Immun Inflamm Dis Year: 2021 Document Type: Article Affiliation country: Iid3.500

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Virus Diseases / Extracellular Traps Limits: Humans Language: English Journal: Immun Inflamm Dis Year: 2021 Document Type: Article Affiliation country: Iid3.500