Role of neutrophils in acute viral infection.
Immun Inflamm Dis
; 9(4): 1186-1196, 2021 12.
Article
in English
| MEDLINE | ID: covidwho-1384181
ABSTRACT
Neutrophils play multiple roles in acute viral infections. They restrict viral replication and diffusion through phagocytosis, degranulation, respiratory burst, secretion of cytokines, and the release of neutrophil extracellular traps, as well as, activate the adaptive immune response. However, the overactivation of neutrophils may cause tissue damage and lead to poor outcomes. Additionally, some characteristics and functions of neutrophils, such as cell number, lifespan, and antiviral capability, can be influenced while eliminating viruses. This review provides a general description of the protective and pathological roles of neutrophils in acute viral infection.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Virus Diseases
/
Extracellular Traps
Limits:
Humans
Language:
English
Journal:
Immun Inflamm Dis
Year:
2021
Document Type:
Article
Affiliation country:
Iid3.500
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