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Corona Immunitas: study protocol of a nationwide program of SARS-CoV-2 seroprevalence and seroepidemiologic studies in Switzerland.
West, Erin A; Anker, Daniela; Amati, Rebecca; Richard, Aude; Wisniak, Ania; Butty, Audrey; Albanese, Emiliano; Bochud, Murielle; Chiolero, Arnaud; Crivelli, Luca; Cullati, Stéphane; d'Acremont, Valérie; Epure, Adina Mihaela; Fehr, Jan; Flahault, Antoine; Fornerod, Luc; Frank, Irène; Frei, Anja; Michel, Gisela; Gonseth, Semira; Guessous, Idris; Imboden, Medea; Kahlert, Christian R; Kaufmann, Laurent; Kohler, Philipp; Mösli, Nicolai; Paris, Daniel; Probst-Hensch, Nicole; Rodondi, Nicolas; Stringhini, Silvia; Vermes, Thomas; Vollrath, Fabian; Puhan, Milo A.
  • West EA; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Hirschengraben 84, 8001, Zurich, Switzerland.
  • Anker D; Population Health Laboratory (#PopHealthLab), University of Fribourg, Fribourg, Switzerland.
  • Amati R; Institute of Public Health, Università Della Svizzera Italiana, Lugano, Switzerland.
  • Richard A; Unit of Population Epidemiology, Division of Primary Care Medicine, Geneva University Hospitals, Geneva, Switzerland.
  • Wisniak A; Institute of Global Health, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
  • Butty A; Unit of Population Epidemiology, Division of Primary Care Medicine, Geneva University Hospitals, Geneva, Switzerland.
  • Albanese E; Institute of Global Health, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
  • Bochud M; Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.
  • Chiolero A; Institute of Public Health, Università Della Svizzera Italiana, Lugano, Switzerland.
  • Crivelli L; Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.
  • Cullati S; Population Health Laboratory (#PopHealthLab), University of Fribourg, Fribourg, Switzerland.
  • d'Acremont V; Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.
  • Epure AM; Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Canada.
  • Fehr J; Institute of Public Health, Università Della Svizzera Italiana, Lugano, Switzerland.
  • Flahault A; Department of Business Economics, Health and Social Care, University of Applied Sciences and Arts of Southern Switzerland, Manno, Switzerland.
  • Fornerod L; Population Health Laboratory (#PopHealthLab), University of Fribourg, Fribourg, Switzerland.
  • Frank I; Department of Readaptation and Geriatrics, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
  • Frei A; Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.
  • Michel G; Swiss Tropical and Public Health Institute, Basel, Switzerland.
  • Gonseth S; University of Basel, Basel, Switzerland.
  • Guessous I; Population Health Laboratory (#PopHealthLab), University of Fribourg, Fribourg, Switzerland.
  • Imboden M; Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.
  • Kahlert CR; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Hirschengraben 84, 8001, Zurich, Switzerland.
  • Kaufmann L; Institute of Global Health, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
  • Kohler P; Health Observatory of Valais, Sion, Switzerland.
  • Mösli N; Clinical Trial Unit, Cantonal Hospital Luzern, Luzern, Switzerland.
  • Paris D; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Hirschengraben 84, 8001, Zurich, Switzerland.
  • Probst-Hensch N; Department of Health Sciences and Medicine, University of Luzern, Luzern, Switzerland.
  • Rodondi N; Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.
  • Stringhini S; Unit of Population Epidemiology, Division of Primary Care Medicine, Geneva University Hospitals, Geneva, Switzerland.
  • Vermes T; Swiss Tropical and Public Health Institute, Basel, Switzerland.
  • Vollrath F; University of Basel, Basel, Switzerland.
  • Puhan MA; Department of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.
Int J Public Health ; 65(9): 1529-1548, 2020 Dec.
Article in English | MEDLINE | ID: covidwho-1384326
ABSTRACT

OBJECTIVES:

Seroprevalence studies to assess the spread of SARS-CoV-2 infection in the general population and subgroups are key for evaluating mitigation and vaccination policies and for understanding the spread of the disease both on the national level and for comparison with the international community.

METHODS:

Corona Immunitas is a research program of coordinated, population-based, seroprevalence studies implemented by Swiss School of Public Health (SSPH+). Over 28,340 participants, randomly selected and age-stratified, with some regional specificities will be included. Additional studies in vulnerable and highly exposed subpopulations are also planned. The studies will assess population immunological status during the pandemic.

RESULTS:

Phase one (first wave of pandemic) estimates from Geneva showed a steady increase in seroprevalence up to 10.8% (95% CI 8.2-13.9, n = 775) by May 9, 2020. Since June, Zurich, Lausanne, Basel City/Land, Ticino, and Fribourg recruited a total of 5973 participants for phase two thus far.

CONCLUSIONS:

Corona Immunitas will generate reliable, comparable, and high-quality serological and epidemiological data with extensive coverage of Switzerland and of several subpopulations, informing health policies and decision making in both economic and societal sectors. ISRCTN Registry https//www.isrctn.com/ISRCTN18181860 .
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Seroepidemiologic Studies / SARS-CoV-2 / COVID-19 / Antibodies, Viral Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Adolescent / Adult / Aged / Child / Humans / Middle aged / Young adult Country/Region as subject: Europa Language: English Journal: Int J Public Health Journal subject: Public Health Year: 2020 Document Type: Article Affiliation country: S00038-020-01494-0

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Seroepidemiologic Studies / SARS-CoV-2 / COVID-19 / Antibodies, Viral Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Adolescent / Adult / Aged / Child / Humans / Middle aged / Young adult Country/Region as subject: Europa Language: English Journal: Int J Public Health Journal subject: Public Health Year: 2020 Document Type: Article Affiliation country: S00038-020-01494-0