Whole genome sequencing and phylogenetic classification of Tunisian SARS-CoV-2 strains from patients of the Military Hospital in Tunis.
Virus Genes
; 56(6): 767-771, 2020 Dec.
Article
in English
| MEDLINE | ID: covidwho-1384547
ABSTRACT
In the present work, two complete genome sequences of SARS-CoV-2 were obtained from nasal swab samples of Tunisian SARS-CoV-2 PCR-positive patients using nanopore sequencing. The virus genomes of two of the patients examined, a Tunisian soldier returning from a mission in Morocco and a member of another Tunisian family, showed significant differences in analyses of the total genome and single nucleotide polymorphisms (SNPs). Phylogenetic relationships with known SARS-CoV-2 genomes in the African region, some European and Middle Eastern countries and initial epidemiological conclusions indicate that the introduction of SARS-CoV-2 into Tunisia from two independent sources was travel-related.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Phylogeny
/
Genome, Viral
/
Pandemics
/
SARS-CoV-2
/
COVID-19
Type of study:
Case report
/
Diagnostic study
/
Observational study
/
Randomized controlled trials
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Africa
/
Europa
Language:
English
Journal:
Virus Genes
Journal subject:
Molecular Biology
/
Virology
Year:
2020
Document Type:
Article
Affiliation country:
S11262-020-01795-9
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