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Can preprocedural mouthrinses reduce SARS-CoV-2 load in dental aerosols?
Reis, Isabella Neme Ribeiro; do Amaral, Guilherme Castro Lima Silva; Mendoza, Aldrin André Huamán; das Graças, Yasmin Teixeira; Mendes-Correa, Maria Cássia; Romito, Giuseppe Alexandre; Pannuti, Claudio Mendes.
  • Reis INR; Department of Estomatology, Division of Periodontology, School of Dentistry, University of São Paulo, Brazil; Institute of Tropical Medicine of São Paulo, Faculty of Medicine, University of São Paulo, Brazil. Electronic address: isabellareis.odonto@gmail.com.
  • do Amaral GCLS; Department of Estomatology, Division of Periodontology, School of Dentistry, University of São Paulo, Brazil; Institute of Tropical Medicine of São Paulo, Faculty of Medicine, University of São Paulo, Brazil. Electronic address: guilhermeclsa@hotmail.com.
  • Mendoza AAH; Department of Estomatology, Division of Periodontology, School of Dentistry, University of São Paulo, Brazil; Institute of Tropical Medicine of São Paulo, Faculty of Medicine, University of São Paulo, Brazil. Electronic address: aldrinhm@usp.br.
  • das Graças YT; Department of Estomatology, Division of Periodontology, School of Dentistry, University of São Paulo, Brazil; Institute of Tropical Medicine of São Paulo, Faculty of Medicine, University of São Paulo, Brazil. Electronic address: yasmindasgracas@gmail.com.
  • Mendes-Correa MC; Department of Estomatology, Division of Periodontology, School of Dentistry, University of São Paulo, Brazil; Institute of Tropical Medicine of São Paulo, Faculty of Medicine, University of São Paulo, Brazil. Electronic address: maria.cassia@hc.fm.usp.br.
  • Romito GA; Department of Estomatology, Division of Periodontology, School of Dentistry, University of São Paulo, Brazil; Institute of Tropical Medicine of São Paulo, Faculty of Medicine, University of São Paulo, Brazil. Electronic address: garomito@usp.br.
  • Pannuti CM; Department of Estomatology, Division of Periodontology, School of Dentistry, University of São Paulo, Brazil; Institute of Tropical Medicine of São Paulo, Faculty of Medicine, University of São Paulo, Brazil. Electronic address: pannuti@usp.br.
Med Hypotheses ; 146: 110436, 2021 Jan.
Article in English | MEDLINE | ID: covidwho-1386311
ABSTRACT
Dental professionals work closely with patients and present an increased risk of person-to-person transmission of SARS-CoV-2. Moreover, the use of ultrasonic scalers, air-water syringes, and slow and high-speed handpieces, which are common in the dental office, generate spatter and aerosol. The use of preprocedural mouthrinses has been proposed to reduce the viral load in saliva and oropharyngeal tissues, thus decreasing viral load in dental aerosol. Although some mouthrinses demonstrates an antiviral effect, there is limited evidence about the clinical efficacy of any mouthrinse in the reduction of SARS-CoV-2 in the dental aerosol. We hypothesized that mouthrinses may reduce SARS-CoV-2 viral load in the oropharynx and its fluids reducing viral load in dental aerosol. The potential use of mouthrinses is discussed, along with proposal of in vitro and clinical studies, in order to evaluate this hypothesis. If this hypothesis holds true, dental professionals and patients may benefit from the routine use of preprocedural mouthrinses.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Infectious Disease Transmission, Patient-to-Professional / Viral Load / SARS-CoV-2 / COVID-19 / Models, Biological / Mouthwashes Type of study: Experimental Studies / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: Med Hypotheses Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Infectious Disease Transmission, Patient-to-Professional / Viral Load / SARS-CoV-2 / COVID-19 / Models, Biological / Mouthwashes Type of study: Experimental Studies / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: Med Hypotheses Year: 2021 Document Type: Article