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COVIDStrategyCalculator: A software to assess testing and quarantine strategies for incoming travelers, contact management, and de-isolation.
van der Toorn, Wiep; Oh, Djin-Ye; von Kleist, Max.
  • van der Toorn W; Systems Medicine of Infectious Disease (P5), Robert Koch Institute, Berlin, Germany.
  • Oh DY; Bioinformatics (MF1), Methodology and Research Infrastructure, Robert Koch Institute, Berlin, Germany.
  • von Kleist M; FG17 Influenza and Other Respiratory Viruses, Department of Infectious Diseases, Robert Koch Institute, Berlin, Germany.
Patterns (N Y) ; 2(6): 100264, 2021 Jun 11.
Article in English | MEDLINE | ID: covidwho-1386425
Semantic information from SemMedBD (by NLM)
1. Quarantine TREATS contact person
Subject
Quarantine
Predicate
TREATS
Object
contact person
2. Infected PROCESS_OF Persons
Subject
Infected
Predicate
PROCESS_OF
Object
Persons
3. Decision PROCESS_OF Maker (occupation)
Subject
Decision
Predicate
PROCESS_OF
Object
Maker (occupation)
4. Quarantine TREATS contact person
Subject
Quarantine
Predicate
TREATS
Object
contact person
5. Infected PROCESS_OF Persons
Subject
Infected
Predicate
PROCESS_OF
Object
Persons
6. Decision PROCESS_OF Maker (occupation)
Subject
Decision
Predicate
PROCESS_OF
Object
Maker (occupation)
ABSTRACT
While large-scale vaccination campaigns against SARS-CoV-2 are rolled out at the time of writing, non-pharmaceutical interventions (NPIs), including the isolation of infected individuals and quarantine of exposed individuals, remain central measures to contain the spread of SARS-CoV-2. Strategies that combine NPIs with innovative SARS-CoV-2 testing strategies may increase containment efficacy and help to shorten quarantine durations. We developed a user-friendly software tool that implements a recently published stochastic within-host viral dynamics model that captures temporal attributes of the viral infection, such as test sensitivity, infectiousness, and the occurrence of symptoms. Based on this model, the software allows to evaluate the efficacy of user-defined, arbitrary NPI and testing strategies in reducing the transmission potential in different contexts. The software thus enables decision makers to explore NPI strategies and perform hypothesis testing, e.g., with regard to the utilization of novel diagnostics or with regard to containing novel virus variants.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Topics: Vaccines / Variants Language: English Journal: Patterns (N Y) Year: 2021 Document Type: Article Affiliation country: J.PATTER.2021.100264

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Topics: Vaccines / Variants Language: English Journal: Patterns (N Y) Year: 2021 Document Type: Article Affiliation country: J.PATTER.2021.100264