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Characteristics of Patients With Immune-Mediated Inflammatory Diseases Hospitalized for SARS-CoV-2 Infection. / Características de pacientes con enfermedades inflamatorias inmunomediadas hospitalizados por infección por SARS-CoV-2.
Robustillo-Villarino, Montserrat; Álvarez-Arroyo, Laura; Carrera-Hueso, Francisco Javier; Barreda-Altaba, Inés; Nieto-Cid, María; Girona-Sanz, Ana María; El-Qutob, David.
  • Robustillo-Villarino M; Sección de Reumatología, Servicio de Medicina Interna, Hospital Universitario de la Plana, Villarreal, Castellón, España. Electronic address: montse.robustillo@gmail.com.
  • Álvarez-Arroyo L; Servicio de Farmacia, Hospital Universitario de la Plana, Villarreal, Castellón, España; Programa de doctorado en Farmacia, Universidad de Granada, Granada, España.
  • Carrera-Hueso FJ; Servicio de Farmacia, Hospital Universitario de la Plana, Villarreal, Castellón, España.
  • Barreda-Altaba I; Servicio de Neurofisiología, Hospital Universitario de la Plana, Villarreal, Castellón, España.
  • Nieto-Cid M; Unidad de Alergología, Servicio de Medicina Interna, Hospital Universitario de la Plana, Villarreal, Castellón, España.
  • Girona-Sanz AM; Sección de Medicina Digestiva, Servicio de Medicina Interna, Hospital Universitario de la Plana, Villarreal, Castellón, España.
  • El-Qutob D; Unidad de Alergología, Servicio de Medicina Interna, Hospital Universitario de la Plana, Villarreal, Castellón, España.
Reumatol Clin (Engl Ed) ; 2021 Mar 20.
Article in English, Spanish | MEDLINE | ID: covidwho-1386553
ABSTRACT

BACKGROUND:

Immune-mediated inflammatory diseases (IMID) predispose to a higher infection risk by modifying the host's immune response, which acts as a key factor in SARS-CoV-2 infection resolution. Recent publications show that IMID patients and its treatments do not worsen the outcome of SARS-CoV-2 infection.

OBJECTIVES:

To describe the clinical characteristics and outcomes of patients with IMID who required hospital admission due to SARS-CoV-2 infection. Secondly, to compare clinical characteristics and outcomes between patients who required hospital admission due to SARS-CoV-2 infection with IMID and those who were not affected.

METHODS:

We performed an observational retrospective cohort study, including admitted patients with suspected SARS-CoV-2 infection, treated according to medical criteria and local protocols based on the best available scientific evidence. Clinical data were collected from their electronical clinical history. Statistical analysis determined the differences in the characteristics and clinical outcome of the infection in IMID patients.

RESULTS:

Of a total number of 612 revised patients, 23 had an IMID and 9 of them were positive for the SARS-CoV-2 infection. We did not observe a correlation between these two disorders. There was a higher frequency of obesity and cardiovascular disease among IMID patients, but without statistical significance. The clinical outcomes were no different between hospitalized IMID and non IMID patients.

CONCLUSION:

IMID and its treatments do not determine the outcome of patients admitted with SARS-CoV-2 infection.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Observational study / Prognostic study Language: English / Spanish Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Observational study / Prognostic study Language: English / Spanish Year: 2021 Document Type: Article