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The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin.
Xia, Shuai; Lan, Qiaoshuai; Su, Shan; Wang, Xinling; Xu, Wei; Liu, Zezhong; Zhu, Yun; Wang, Qian; Lu, Lu; Jiang, Shibo.
  • Xia S; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China.
  • Lan Q; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China.
  • Su S; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China.
  • Wang X; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China.
  • Xu W; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China.
  • Liu Z; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China.
  • Zhu Y; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
  • Wang Q; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China. wang_qian@fudan.edu.cn.
  • Lu L; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China. lul@fudan.edu.cn.
  • Jiang S; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, 130 Dong An Road, Shanghai, 200032, China. shibojiang@fudan.edu.cn.
Signal Transduct Target Ther ; 5(1): 92, 2020 06 12.
Article in English | MEDLINE | ID: covidwho-1387187
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Trypsin / Signal Transduction / Severe acute respiratory syndrome-related coronavirus / Furin / Spike Glycoprotein, Coronavirus / Betacoronavirus Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2020 Document Type: Article Affiliation country: S41392-020-0184-0

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Trypsin / Signal Transduction / Severe acute respiratory syndrome-related coronavirus / Furin / Spike Glycoprotein, Coronavirus / Betacoronavirus Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2020 Document Type: Article Affiliation country: S41392-020-0184-0