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Main protease of SARS-CoV-2 serves as a bifunctional molecule in restricting type I interferon antiviral signaling.
Wu, Yaoxing; Ma, Ling; Zhuang, Zhen; Cai, Sihui; Zhao, Zhiyao; Zhou, Lingli; Zhang, Jing; Wang, Pei-Hui; Zhao, Jincun; Cui, Jun.
  • Wu Y; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, 510275, Guangzhou, Guangdong, China.
  • Ma L; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, 510275, Guangzhou, Guangdong, China.
  • Zhuang Z; State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, 510182, Guangzhou, Guangdong, China.
  • Cai S; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, 510275, Guangzhou, Guangdong, China.
  • Zhao Z; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, 510275, Guangzhou, Guangdong, China.
  • Zhou L; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, 510275, Guangzhou, Guangdong, China.
  • Zhang J; Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, 250012, Jinan, Shandong, China.
  • Wang PH; Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, 250012, Jinan, Shandong, China.
  • Zhao J; State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, 510182, Guangzhou, Guangdong, China. zhaojincun@gird.cn.
  • Cui J; MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, 510275, Guangzhou, Guangdong, China. cuij5@mail.sysu.edu.cn.
Signal Transduct Target Ther ; 5(1): 221, 2020 10 06.
Article in English | MEDLINE | ID: covidwho-1387195
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Cysteine Endopeptidases / Signal Transduction / Interferon-beta / Interferon-alpha / Viral Nonstructural Proteins / Host-Pathogen Interactions / Betacoronavirus Language: English Journal: Signal Transduct Target Ther Year: 2020 Document Type: Article Affiliation country: S41392-020-00332-2

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Cysteine Endopeptidases / Signal Transduction / Interferon-beta / Interferon-alpha / Viral Nonstructural Proteins / Host-Pathogen Interactions / Betacoronavirus Language: English Journal: Signal Transduct Target Ther Year: 2020 Document Type: Article Affiliation country: S41392-020-00332-2