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Identification of bis-benzylisoquinoline alkaloids as SARS-CoV-2 entry inhibitors from a library of natural products.
He, Chang-Long; Huang, Lu-Yi; Wang, Kai; Gu, Chen-Jian; Hu, Jie; Zhang, Gui-Ji; Xu, Wei; Xie, You-Hua; Tang, Ni; Huang, Ai-Long.
  • He CL; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
  • Huang LY; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
  • Wang K; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
  • Gu CJ; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.
  • Hu J; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
  • Zhang GJ; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
  • Xu W; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.
  • Xie YH; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, China. yhxie@fudan.edu.cn.
  • Tang N; Children's Hospital, Fudan University, Shanghai, China. yhxie@fudan.edu.cn.
  • Huang AL; Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China. nitang@cqmu.edu.cn.
Signal Transduct Target Ther ; 6(1): 131, 2021 03 23.
Article in English | MEDLINE | ID: covidwho-1387212

Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Benzylisoquinolines / Alkaloids / Virus Internalization / Small Molecule Libraries / SARS-CoV-2 Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2021 Document Type: Article Affiliation country: S41392-021-00531-5

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Benzylisoquinolines / Alkaloids / Virus Internalization / Small Molecule Libraries / SARS-CoV-2 Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2021 Document Type: Article Affiliation country: S41392-021-00531-5