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Identification of SARS-CoV-2-against aptamer with high neutralization activity by blocking the RBD domain of spike protein 1.
Yang, Ge; Li, Ziyue; Mohammed, Irfan; Zhao, Liping; Wei, Wei; Xiao, Haihua; Guo, Weisheng; Zhao, Yongxiang; Qu, Feng; Huang, Yuanyu.
  • Yang G; School of Life Science; Advanced Research Institute of Multidisciplinary Science; Institute of Engineering Medicine; Key Laboratory of Molecular Medicine and Biotherapy, Beijing Institute of Technology, Beijing, China.
  • Li Z; School of Life Science; Advanced Research Institute of Multidisciplinary Science; Institute of Engineering Medicine; Key Laboratory of Molecular Medicine and Biotherapy, Beijing Institute of Technology, Beijing, China.
  • Mohammed I; School of Life Science; Advanced Research Institute of Multidisciplinary Science; Institute of Engineering Medicine; Key Laboratory of Molecular Medicine and Biotherapy, Beijing Institute of Technology, Beijing, China.
  • Zhao L; School of Life Science; Advanced Research Institute of Multidisciplinary Science; Institute of Engineering Medicine; Key Laboratory of Molecular Medicine and Biotherapy, Beijing Institute of Technology, Beijing, China.
  • Wei W; State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, China.
  • Xiao H; Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
  • Guo W; Translational Medicine Center, Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & the Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
  • Zhao Y; National Center for International Research of Biological Targeting Diagnosis and Therapy, Guangxi Key Laboratory of Biological Targeting Diagnosis and Therapy Research, Guangxi Medical University, Nanning, Guangxi, China.
  • Qu F; School of Life Science; Advanced Research Institute of Multidisciplinary Science; Institute of Engineering Medicine; Key Laboratory of Molecular Medicine and Biotherapy, Beijing Institute of Technology, Beijing, China.
  • Huang Y; School of Life Science; Advanced Research Institute of Multidisciplinary Science; Institute of Engineering Medicine; Key Laboratory of Molecular Medicine and Biotherapy, Beijing Institute of Technology, Beijing, China. yyhuang@bit.edu.cn.
Signal Transduct Target Ther ; 6(1): 227, 2021 06 10.
Article in English | MEDLINE | ID: covidwho-1387231
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Aptamers, Nucleotide / Spike Glycoprotein, Coronavirus / SARS-CoV-2 / COVID-19 Drug Treatment Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2021 Document Type: Article Affiliation country: S41392-021-00649-6

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Aptamers, Nucleotide / Spike Glycoprotein, Coronavirus / SARS-CoV-2 / COVID-19 Drug Treatment Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2021 Document Type: Article Affiliation country: S41392-021-00649-6