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The real seroprevalence of SARS-CoV-2 in France and its consequences for virus dynamics.
Dimeglio, Chloé; Loubes, Jean-Michel; Miedougé, Marcel; Herin, Fabrice; Soulat, Jean-Marc; Izopet, Jacques.
  • Dimeglio C; 2 INSERM UMR1291 - CNRS UMR5051, Toulouse Institute for Infectious and Inflammatory Diseases (INFINITy), 31300, Toulouse, France. dimeglio.c@chu-toulouse.fr.
  • Loubes JM; Virology Laboratory, CHU Toulouse, Hôpital Purpan, 31300, Toulouse, France. dimeglio.c@chu-toulouse.fr.
  • Miedougé M; Institut de Mathématiques de Toulouse, Université de Toulouse, 31400, Toulouse, France.
  • Herin F; Virology Laboratory, CHU Toulouse, Hôpital Purpan, 31300, Toulouse, France.
  • Soulat JM; Occupational Diseases Department, Toulouse-Purpan University Hospital, 31000, Toulouse, France.
  • Izopet J; Occupational Diseases Department, Toulouse-Purpan University Hospital, 31000, Toulouse, France.
Sci Rep ; 11(1): 12597, 2021 06 15.
Article in English | MEDLINE | ID: covidwho-1387480
ABSTRACT
The SARS-CoV-2 virus has spread world-wide since December 2019, killing more than 2.9 million of people. We have adapted a statistical model from the SIR epidemiological models to predict the spread of SARS-CoV-2 in France. Our model is based on several parameters and assumed a 4.2% seroprevalence in Occitania after the first lockdown. The recent use of serological tests to measure the effective seroprevalence of SARS-CoV-2 in the population of Occitania has led to a seroprevalence around 2.4%. This implies to review the parameters of our model to conclude at a lower than expected virus transmission rate, which may be due to infectivity varying with the patient's symptoms or to a constraint due to an uneven population geographical distribution.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Serological Testing / COVID-19 Type of study: Observational study / Prognostic study Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Sci Rep Year: 2021 Document Type: Article Affiliation country: S41598-021-92131-0

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Serological Testing / COVID-19 Type of study: Observational study / Prognostic study Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Sci Rep Year: 2021 Document Type: Article Affiliation country: S41598-021-92131-0