Letter to the Editor: Significant mutation enrichment in inverted repeat sites of new SARS-CoV-2 strains.
Brief Bioinform
; 22(5)2021 09 02.
Article
in English
| MEDLINE | ID: covidwho-1387714
ABSTRACT
In a recently published paper, we have found that SARS-CoV-2 hot-spot mutations are significantly associated with inverted repeat loci and CG dinucleotides. However, fast-spreading strains with new mutations (so-called mink farm mutations, England mutations and Japan mutations) have been recently described. We used the new datasets to check the positioning of mutation sites in genomes of the new SARS-CoV-2 strains. Using an open-access Palindrome analyzer tool, we found mutations in these new strains to be significantly enriched in inverted repeat loci.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
SARS-CoV-2
/
Mutation
Limits:
Humans
Language:
English
Journal subject:
Biology
/
Medical Informatics
Year:
2021
Document Type:
Article
Affiliation country:
BIB
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