Multisystem Inflammatory Syndrome in Children Associated With Severe Acute Respiratory Syndrome Coronavirus-2 in an 8-Week-Old Infant.
J Pediatric Infect Dis Soc
; 9(6): 781-784, 2020 Dec 31.
Article
in English
| MEDLINE | ID: covidwho-1387931
ABSTRACT
We describe an 8-week-old infant with severe gastrointestinal symptoms, significant hypoalbuminemia, and mild carditis following asymptomatic infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The infant's symptoms, including their temporal appearance, were consistent with multisystem inflammatory syndrome in children (MIS-C). A unique finding on colonic histology which may shed light on the pathogenesis of MIS-C was identified. The patient improved significantly following several anti-inflammatory treatments. The lag between the presentation of MIS-C and initial SARS-CoV-2 exposure, which may often be asymptomatic, together with the young age of our patient, makes this a challenging diagnosis. Clinicians should be aware of this entity, even in the neonatal and infantile age groups, to facilitate timely identification and treatment.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Systemic Inflammatory Response Syndrome
/
COVID-19
Type of study:
Case report
/
Diagnostic study
/
Experimental Studies
/
Randomized controlled trials
Limits:
Female
/
Humans
/
Infant
Language:
English
Journal:
J Pediatric Infect Dis Soc
Year:
2020
Document Type:
Article
Affiliation country:
JPIDS
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