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Comparative Analysis of Capillary vs Venous Blood for Serologic Detection of SARS-CoV-2 Antibodies by RPOC Lateral Flow Tests.
Morshed, Muhammad; Sekirov, Inna; McLennan, Meghan; Levett, Paul N; Chahil, Navdeep; Mak, Annie; Carruthers, Erin; Pidduck, Tamara; Kustra, Jesse; Laley, Jonathan; Lee, Min-Kuang; Chu, Kenneth; Burgess, Fred; Vijh, Rohit; Willis, Lori; Wada, Ray; Blancaflor, Rosemarie; Boraston, Suni; Hayden, Althea; Krajden, Mel.
  • Morshed M; British Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
  • Sekirov I; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • McLennan M; British Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
  • Levett PN; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • Chahil N; Provincial Laboratory Medicine Services, Provincial Health Services Authority, Vancouver, British Columbia, Canada.
  • Mak A; British Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
  • Carruthers E; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • Pidduck T; British Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
  • Kustra J; British Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
  • Laley J; British Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
  • Lee MK; British Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
  • Chu K; British Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
  • Burgess F; British Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
  • Vijh R; British Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
  • Willis L; British Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
  • Wada R; British Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
  • Blancaflor R; School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada.
  • Boraston S; British Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
  • Hayden A; British Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
  • Krajden M; British Columbia Centre for Disease Control Public Health Laboratory, Vancouver, British Columbia, Canada.
Open Forum Infect Dis ; 8(3): ofab043, 2021 Mar.
Article in English | MEDLINE | ID: covidwho-1387998
ABSTRACT
A comparison of rapid point-of-care serology tests using finger prick and venous blood was done on 278 participants. In a laboratory setting, immunoglobulin G (IgG) sensitivity neared 100%; however, IgG sensitivity dramatically dropped (82%) in field testing. Possible factors include finger prick volume variability, hemolysis, cassette readability, and operator training.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Diagnostic study Language: English Journal: Open Forum Infect Dis Year: 2021 Document Type: Article Affiliation country: OFID

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Diagnostic study Language: English Journal: Open Forum Infect Dis Year: 2021 Document Type: Article Affiliation country: OFID