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The influence of the SARS-CoV-2 lockdown on patients with inflammatory rheumatic diseases on their adherence to immunomodulatory medication: a cross sectional study over 3 months in Germany.
Hasseli, R; Müller-Ladner, U; Keil, F; Broll, M; Dormann, A; Fräbel, C; Hermann, W; Heinmüller, C-J; Hoyer, B F; Löffler, F; Özden, F; Pfeiffer, U; Saech, J; Schneidereit, T; Schlesinger, A; Schwarting, A; Specker, C; Stapfer, G; Steinmüller, M; Storck-Müller, K; Strunk, J; Thiele, A; Triantafyllias, K; Vagedes, D; Wassenberg, S; Wilden, E; Zeglam, S; Schmeiser, T.
  • Hasseli R; Department of Rheumatology and Immunology, Campus Kerckhoff, Justus-Liebig-University Giessen, Giessen, Germany.
  • Müller-Ladner U; Department of Rheumatology and Immunology, Campus Kerckhoff, Justus-Liebig-University Giessen, Giessen, Germany.
  • Keil F; Department of Electrical Engineering and Information Technology, Technical University Darmstadt, Darmstadt, Germany.
  • Broll M; Private Practice, Wetzlar, Germany.
  • Dormann A; Department of Rheumatology and Immunology, Saint Josef Hospital, Wuppertal, Germany.
  • Fräbel C; Department of Cardiology, University Hospital Giessen, Justus-Liebig-University Giessen, Giessen, Germany.
  • Hermann W; Department of Rheumatology and Immunology, Campus Kerckhoff, Justus-Liebig-University Giessen, Giessen, Germany.
  • Heinmüller CJ; Private Practice, Wuppertal, Germany.
  • Hoyer BF; Department of Rheumatology and Clinical Immunology, Clinic for Internal Medicine I, University Hospital Schleswig-Holstein, Campus, Kiel, Germany.
  • Löffler F; Department of Rheumatology and Immunology, Campus Kerckhoff, Justus-Liebig-University Giessen, Giessen, Germany.
  • Özden F; Private Practice, Nienburg, Germany.
  • Pfeiffer U; Department of Rheumatology and Immunology, Saint Josef Hospital, Wuppertal, Germany.
  • Saech J; Private Practice 'Rheumatologie-Centrum', Leverkusen, Germany.
  • Schneidereit T; Department of Rheumatology and Immunology, Saint Josef Hospital, Wuppertal, Germany.
  • Schlesinger A; Department of Internal Medicine, Pulmonology and Rheumatology, Marienhospital, Cologne, Germany.
  • Schwarting A; Acura Rheumatology Center Rhineland Palatinate, Bad Kreuznach, Germany.
  • Specker C; Department of Rheumatology and Clinical Immunology, Kliniken Essen-Mitte, Essen, Germany.
  • Stapfer G; Department of Rheumatology and Immunology, Campus Kerckhoff, Justus-Liebig-University Giessen, Giessen, Germany.
  • Steinmüller M; Private Practice, Ehringshausen, Germany.
  • Storck-Müller K; Rheumazentrum Mittelhessen, Bad Endbach, Germany.
  • Strunk J; Department of Rheumatology, Hospital Porz am Rhein, Cologne, Germany.
  • Thiele A; Department of Rheumatology and Immunology, Saint Josef Hospital, Wuppertal, Germany.
  • Triantafyllias K; Acura Rheumatology Center Rhineland Palatinate, Bad Kreuznach, Germany.
  • Vagedes D; Medical Care Centre Barmherzige Brüder, Straubing, Germany.
  • Wassenberg S; Private Practice 'Rheumazentrum Ratingen', Ratingen, Germany.
  • Wilden E; Private Practice, Cologne, Germany.
  • Zeglam S; Department of Internal Medicine, Pulmonology and Rheumatology, Marienhospital, Cologne, Germany.
  • Schmeiser T; Department of Rheumatology and Immunology, Saint Josef Hospital, Wuppertal, Germany.
Rheumatology (Oxford) ; 60(SI): SI51-SI58, 2021 10 09.
Article in English | MEDLINE | ID: covidwho-1388016
ABSTRACT

OBJECTIVES:

To evaluate the influence of the SARS-CoV-2 pandemic on the adherence of patients with inflammatory rheumatic diseases (IRD) to their immunomodulatory medication during the three-month lockdown in Germany.

METHODS:

From 16th March until 15th June 2020, IRD patients from private practices and rheumatology departments were asked to answer a questionnaire addressing their behaviour with respect to their immunomodulating therapy. Eight private practices and nine rheumatology departments that included rheumatology primary care centres and university hospitals participated. A total of 4252 questionnaires were collected and evaluated.

RESULTS:

The majority of patients (54%) were diagnosed with RA, followed by psoriatic arthritis (14%), ankylosing spondylitis (10%), connective tissue diseases (12%) and vasculitides (6%). Most of the patients (84%) reported to continue their immunomodulatory therapy. Termination of therapy was reported by only 3% of the patients. The results were independent from the type of IRD, the respective immunomodulatory therapy and by whom the patients were treated (private practices vs rheumatology departments). Younger patients (<60 years) reported just as often as older patients to discontinue their therapy.

CONCLUSION:

The data show that most of the patients continued their therapy in spite of the pandemic. A significant change in behaviour with regard to their immunomodulatory therapy was not observed during the three months of observation. The results support the idea that the immediate release of recommendations of the German Society of Rheumatology were well received, supporting the well-established physician-patient relationship in times of a crisis.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Drug Prescriptions / Practice Patterns, Physicians&apos; / Quarantine / Rheumatic Diseases / Medication Adherence / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Rheumatology (Oxford) Journal subject: Rheumatology Year: 2021 Document Type: Article Affiliation country: RHEUMATOLOGY

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Drug Prescriptions / Practice Patterns, Physicians&apos; / Quarantine / Rheumatic Diseases / Medication Adherence / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Rheumatology (Oxford) Journal subject: Rheumatology Year: 2021 Document Type: Article Affiliation country: RHEUMATOLOGY