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Correlation of hematological parameters and cycle threshold in ambulatory patients with SARS-CoV-2 infection.
Girón-Pérez, Daniel Alberto; Benitez-Trinidad, Alma Betsaida; Ruiz-Manzano, Rocio Alejandra; Toledo-Ibarra, Gladys Alejandra; Ventura-Ramón, Guadalupe Herminia; Covantes-Rosales, Carlos Eduardo; Ojeda-Durán, Ansonny Jhovany; Díaz-Reséndiz, Karina Janice Guadalupe; Mercado-Salgado, Ulises; Girón-Pérez, Manuel Iván.
  • Girón-Pérez DA; Laboratorio Nacional de Investigación para la Inocuidad Alimentaria (LANIIA) Unidad Nayarit, Universidad Autónoma de Nayarit, Tepic, México.
  • Benitez-Trinidad AB; Laboratorio Nacional de Investigación para la Inocuidad Alimentaria (LANIIA) Unidad Nayarit, Universidad Autónoma de Nayarit, Tepic, México.
  • Ruiz-Manzano RA; Laboratorio Nacional de Investigación para la Inocuidad Alimentaria (LANIIA) Unidad Nayarit, Universidad Autónoma de Nayarit, Tepic, México.
  • Toledo-Ibarra GA; Laboratorio Nacional de Investigación para la Inocuidad Alimentaria (LANIIA) Unidad Nayarit, Universidad Autónoma de Nayarit, Tepic, México.
  • Ventura-Ramón GH; Laboratorio Nacional de Investigación para la Inocuidad Alimentaria (LANIIA) Unidad Nayarit, Universidad Autónoma de Nayarit, Tepic, México.
  • Covantes-Rosales CE; Laboratorio Nacional de Investigación para la Inocuidad Alimentaria (LANIIA) Unidad Nayarit, Universidad Autónoma de Nayarit, Tepic, México.
  • Ojeda-Durán AJ; Laboratorio Nacional de Investigación para la Inocuidad Alimentaria (LANIIA) Unidad Nayarit, Universidad Autónoma de Nayarit, Tepic, México.
  • Díaz-Reséndiz KJG; Laboratorio Nacional de Investigación para la Inocuidad Alimentaria (LANIIA) Unidad Nayarit, Universidad Autónoma de Nayarit, Tepic, México.
  • Mercado-Salgado U; Laboratorio Nacional de Investigación para la Inocuidad Alimentaria (LANIIA) Unidad Nayarit, Universidad Autónoma de Nayarit, Tepic, México.
  • Girón-Pérez MI; Laboratorio Nacional de Investigación para la Inocuidad Alimentaria (LANIIA) Unidad Nayarit, Universidad Autónoma de Nayarit, Tepic, México.
Int J Lab Hematol ; 43(4): 873-880, 2021 Aug.
Article in English | MEDLINE | ID: covidwho-1388288
ABSTRACT

INTRODUCTION:

Former studies have shown that hematologic parameters are affected by the SARS-CoV-2 infection which has caused a global health problem. Therefore, this research aims to identify the most frequent symptoms and comorbidities in SARS-CoV-2 infected outpatients; besides, to analyze hematological parameters and their correlation with cycle threshold (Ct) values.

METHODS:

We analyzed a total of sixty outpatients with SARS-CoV-2 infection. They were divided according to sex. Afterward, a questionnaire was carried out to find out their symptoms and comorbidities. Additionally, blood biometry data were correlated with the Ct value, respectively.

RESULTS:

Sixty patients were analyzed; the mean age was 43 years. All patients were from Nayarit, Mexico. The frequency index showed that the main symptoms were headache and anosmia, and the comorbidities were obesity and smoking. The analysis of blood biometry showed a clear increase in red blood cells (RBC) related parameters in women. In both sexes an increase in the number of white blood cells (WBC) was observed. Also, all the hematological alterations correlated with the grade of infection.

CONCLUSION:

Headache and anosmia are the most common symptoms according to the frequency index, the main comorbidities were obesity and smoking. Also, there is a Ct value correlation with hematological parameters (WBC, mean corpuscular volume, mean corpuscular hemoglobin, hemoglobin); they can be used as a prognostic marker of infection.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study Limits: Adult / Aged / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: Mexico Language: English Journal: Int J Lab Hematol Journal subject: Hematology Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study Limits: Adult / Aged / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: Mexico Language: English Journal: Int J Lab Hematol Journal subject: Hematology Year: 2021 Document Type: Article