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Severe acquired haemophilia associated with asymptomatic SARS-CoV-2 infection.
Wang, Kevin Y; Shah, Pratik; Roarke, Dennis T; Shakil, Shams A.
  • Wang KY; Department of Internal Medicine, NSLIJ Health System, New Hyde Park, New York, USA Kevwangyu@gmail.com.
  • Shah P; Department of Internal Medicine, NSLIJ Health System, New Hyde Park, New York, USA.
  • Roarke DT; Department of Internal Medicine, Northwell Health, New Hyde Park, New York, USA.
  • Shakil SA; Department of Hematology Oncology, Northwell Health, New Hyde Park, New York, USA.
BMJ Case Rep ; 14(7)2021 Jul 20.
Article in English | MEDLINE | ID: covidwho-1388480
ABSTRACT
A 65-year-old man presented with symptoms of severe subcutaneous bleeding in his arm, which led to compartment syndrome requiring fasciotomy and massive blood transfusion protocol. Medical history was significant for history of autoimmune thyroid disease. Workup revealed elevated partial thromboplastin time, decreased factor VIII levels and elevated factor VIII inhibitor levels. He was worked up for causes of acquired haemophilia A and was found to have an elevated SARS-CoV-2 antibody level. Given his negative workup for other secondary aetiologies, we suspect that the cause of his haemophilia A was from his SARS-CoV-2 infection, which has been observed previously in various case reports.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Hemophilia A Type of study: Case report / Diagnostic study / Etiology study / Prognostic study Topics: Long Covid Limits: Aged / Humans / Male Language: English Year: 2021 Document Type: Article Affiliation country: BCR-2021-242884

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Hemophilia A Type of study: Case report / Diagnostic study / Etiology study / Prognostic study Topics: Long Covid Limits: Aged / Humans / Male Language: English Year: 2021 Document Type: Article Affiliation country: BCR-2021-242884