rfaRm: An R client-side interface to facilitate the analysis of the Rfam database of RNA families.
PLoS One
; 16(1): e0245280, 2021.
Article
in English
| MEDLINE | ID: covidwho-1388897
ABSTRACT
rfaRm is an R package providing a client-side interface for the Rfam database of non-coding RNA and other structured RNA elements. The package facilitates the search of the Rfam database by keywords or sequences, as well as the retrieval of all available information about specific Rfam families, such as member sequences, multiple sequence alignments, secondary structures and covariance models. By providing such programmatic access to the Rfam database, rfaRm enables genomic workflows to incorporate information about non-coding RNA, whose potential cannot be fully exploited just through interactive access to the database. The features of rfaRm are demonstrated by using it to analyze the SARS-CoV-2 genome as an example case.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Software
/
Sequence Analysis, RNA
/
RNA, Untranslated
Limits:
Humans
Language:
English
Journal:
PLoS One
Journal subject:
Science
/
Medicine
Year:
2021
Document Type:
Article
Affiliation country:
JOURNAL.PONE.0245280
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