Dual targeting of Toll-like receptor 4 and angiotensin-converting enzyme 2: a proposed approach to SARS-CoV-2 treatment.

Kate Gadanec, Laura; Qaradakhi, Tawar; Renee McSweeney, Kristen; Ashiana Ali, Benazir; Zulli, Anthony; Apostolopoulos, Vasso

Dual targeting of Toll-like receptor 4 and angiotensin-converting enzyme 2: a proposed approach to SARS-CoV-2 treatment.

Kate Gadanec, Laura; Qaradakhi, Tawar; Renee McSweeney, Kristen; Ashiana Ali, Benazir; Zulli, Anthony; Apostolopoulos, Vasso.

Kate Gadanec L; Institute for Health & Sport, Victoria University, Melbourne, Australia.
Qaradakhi T; Institute for Health & Sport, Victoria University, Melbourne, Australia.
Renee McSweeney K; Institute for Health & Sport, Victoria University, Melbourne, Australia.
Ashiana Ali B; Institute for Health & Sport, Victoria University, Melbourne, Australia.
Zulli A; Institute for Health & Sport, Victoria University, Melbourne, Australia.
Apostolopoulos V; Institute for Health & Sport, Victoria University, Melbourne, Australia.

Future Microbiol ; 16: 205-209, 2021 03.

Article in English | MEDLINE | ID: covidwho-1389072

Subject(s)

Angiotensin-Converting Enzyme 2/metabolism; Antiviral Agents/pharmacology; COVID-19 Drug Treatment; Toll-Like Receptor 4/antagonists & inhibitors; Anti-Inflammatory Agents/pharmacology; Anti-Inflammatory Agents/therapeutic use; Antiviral Agents/therapeutic use; COVID-19/metabolism; COVID-19/virology; Enzyme Activators/pharmacology; Enzyme Activators/therapeutic use; Humans; Inflammation/drug therapy; Inflammation/virology; Molecular Targeted Therapy; SARS-CoV-2/drug effects; SARS-CoV-2/isolation & purification; Sulfonamides/pharmacology; Sulfonamides/therapeutic use; Toll-Like Receptor 4/metabolism

Keywords

ACE2; COVID-19; SARS-CoV-2; TLR4; Toll-like receptor; angiotensin-converting enzyme 2; coronavirus; coronavirus disease 2019

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Toll-Like Receptor 4 / Angiotensin-Converting Enzyme 2 / COVID-19 Drug Treatment Limits: Humans Language: English Journal: Future Microbiol Journal subject: Microbiology Year: 2021 Document Type: Article Affiliation country: FMB-2021-0018

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