A systematic review of contemporary evidence on SARS-CoV-2 and HIV coinfection: What does it look like up to date?
Avicenna J Med
; 10(4): 189-197, 2020.
Article
in English
| MEDLINE | ID: covidwho-1389616
ABSTRACT
BACKGROUND:
Preexisting alteration of the immune system by factors including older age, cardiovascular diseases, morbid obesity, diabetes, and chronic obstructive pulmonary disease (COPD) have detrimental effects on SARS-CoV-2 patients. Literature regarding SARS-CoV-2/human immunodeficiency virus (HIV) is still developing. MATERIALS ANDMETHODS:
We reviewed the existing literature pertaining to SARS-CoV-2/HIV coinfection systematically. Research records' characteristics and patients' clinical data were collected.RESULTS:
Seven research records were included, of which three were case series and four were case reports, reporting a total of 16 cases. There was one case of death, whereas (15/16) patients were discharged home. Majority of patients developed consistent clinical presentation of SARS-CoV-2. All patients had initial positive RT-PCR results, and four cases had HIV-related lymphopenia.CONCLUSION:
Although the current literature is still growing to increase our understanding of SARS-CoV-2/HIV coinfection, people living with HIV should adhere to the guidelines of healthy behavior and practice during this pandemic.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Prognostic study
/
Reviews
/
Systematic review/Meta Analysis
Language:
English
Journal:
Avicenna J Med
Year:
2020
Document Type:
Article
Affiliation country:
AJM.AJM_175_20
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