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[Analysis of the demand for detection of SARSCoV-2 in a health area of Spain]. / Análisis de la demanda de detección de SARS-CoV-2 en un área de salud de España.
García-Cruces, J; López Izquierdo, R; Domínguez-Gil, M; López-Urrutia, L; de Frutos, M; Lorenzo, B; Nogueira, B; Puerta, A; Fernández-Esgueva, M; Merino, I; Ramos Sanchez, M C; Eiros, J M.
  • López Izquierdo R; Raúl López Izquierdo. Servicio de Urgencias Hospital Universitario Río Hortega. Dulzaina nº 2, 47012. Valladolid. Spain. rlopeziz@saludcastillayleon.es.
Rev Esp Quimioter ; 33(6): 422-429, 2020 Dec.
Article in Spanish | MEDLINE | ID: covidwho-1390021
ABSTRACT

OBJECTIVE:

Since the discovery of the SARS-CoV-2 virus, the polymerase chain reaction technique (RT-PCR) has become the fundamental method for diagnosing the disease in its acute phase. The objective is to describe the demand-based series of RT-PCR determinations received at a Microbiology Service at a third-level reference hospital for a health area for three months spanning from the onset of the epidemic by SARS-CoV-2.

METHODS:

A retrospective analysis of the total of the RT-PCR requested in the Microbiology Service analyzed from 02/25/2020 to 05/26/2020 (90 days) has been carried out. They have been grouped by epidemiological weeks and by the petitioner service. A descriptive analysis was carried out by age, gender and number of requests for each patient. In the tests carried out, a confidence level of 95% (p <0.05) was considered significant.

RESULTS:

A total of 27,106 requests was received corresponding to 22,037 patients. Median age 53.7 (RIC 40.9-71.7) years, women 61.3%. Proportion of patients with any positive RT-PCR 14%. Of the total requests for RT-PCR, positive 3,710. Week 13 had the highest diagnosis performance (39.0%). The primary care has been the service thar has made the most requests (15,953). Patients with 3 or more RT-PCR 565, of them, 19 patients had a positive result after previously having a negative one.

CONCLUSIONS:

Requests have been increasing depending on the evolution of the epidemic. The RT-PCR has a high diagnostic performance in the phases of highest contagiousness and / or transmissibility of the virus.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Reverse Transcriptase Polymerase Chain Reaction / Pandemics / SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Observational study Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Country/Region as subject: Europa Language: Spanish Journal: Rev Esp Quimioter Journal subject: Drug Therapy Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Reverse Transcriptase Polymerase Chain Reaction / Pandemics / SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Observational study Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Country/Region as subject: Europa Language: Spanish Journal: Rev Esp Quimioter Journal subject: Drug Therapy Year: 2020 Document Type: Article