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A Review of the Health Protective Effects of Phenolic Acids against a Range of Severe Pathologic Conditions (Including Coronavirus-Based Infections).
Kiokias, Sotirios; Oreopoulou, Vassiliki.
  • Kiokias S; European Research Executive Agency, Place Charles Rogier 16, 1210 Bruxelles, Belgium.
  • Oreopoulou V; Laboratory of Food Chemistry and Technology, School of Chemical Engineering, National Technical University of Athens, Iron Politechniou 9, 15780 Athens, Greece.
Molecules ; 26(17)2021 Sep 06.
Article in English | MEDLINE | ID: covidwho-1390161
ABSTRACT
Phenolic acids comprise a class of phytochemical compounds that can be extracted from various plant sources and are well known for their antioxidant and anti-inflammatory properties. A few of the most common naturally occurring phenolic acids (i.e., caffeic, carnosic, ferulic, gallic, p-coumaric, rosmarinic, vanillic) have been identified as ingredients of edible botanicals (thyme, oregano, rosemary, sage, mint, etc.). Over the last decade, clinical research has focused on a number of in vitro (in human cells) and in vivo (animal) studies aimed at exploring the health protective effects of phenolic acids against the most severe human diseases. In this review paper, the authors first report on the main structural features of phenolic acids, their most important natural sources and their extraction techniques. Subsequently, the main target of this analysis is to provide an overview of the most recent clinical studies on phenolic acids that investigate their health effects against a range of severe pathologic conditions (e.g., cancer, cardiovascular diseases, hepatotoxicity, neurotoxicity, and viral infections-including coronaviruses-based ones).
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Plant Extracts / Cinnamates / Hydroxybenzoates / Anti-Inflammatory Agents / Antioxidants Type of study: Diagnostic study / Experimental Studies / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal subject: Biology Year: 2021 Document Type: Article Affiliation country: Molecules26175405

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Plant Extracts / Cinnamates / Hydroxybenzoates / Anti-Inflammatory Agents / Antioxidants Type of study: Diagnostic study / Experimental Studies / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal subject: Biology Year: 2021 Document Type: Article Affiliation country: Molecules26175405