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Nuts and bolts of COVID-19 associated coagulopathy: the essentials for management and treatment.
Lindsay, Patrick J; Rosovsky, Rachel; Bittner, Edward A; Chang, Marvin G.
  • Lindsay PJ; Department of Critical Care, Cleveland Clinic, Cleveland, Ohio, USA.
  • Rosovsky R; Division of Hematology & Oncology, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Bittner EA; Department of Anesthesia Critical Care and Pain, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Chang MG; Department of Anesthesia Critical Care and Pain, Massachusetts General Hospital, Boston, Massachusetts, USA.
Postgrad Med ; 133(8): 899-911, 2021 Nov.
Article in English | MEDLINE | ID: covidwho-1390265
ABSTRACT

INTRODUCTION:

COVID-19-associated coagulopathy (CAC) is a well-recognized hematologic complication among patients with severe COVID-19 disease, where macro- and micro-thrombosis can lead to multiorgan injury and failure. Major societal guidelines that have published on the management of CAC are based on consensus of expert opinion, with the current evidence available. As a result of limited studies, there are many clinical scenarios that are yet to be addressed, with expert opinion varying on a number of important clinical issues regarding CAC management.

METHODS:

In this review, we utilize current societal guidelines to provide a framework for practitioners in managing their patients with CAC. We have also provided three clinical scenarios that implement important principles of anticoagulation in patients with COVID-19.

CONCLUSION:

Overall, decisions should be made on acase by cases basis and based on the providers understanding of each patient's medical history, clinical course and perceived risk.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Thromboembolism / Thrombosis / Blood Coagulation Disorders / Practice Guidelines as Topic / COVID-19 / Anticoagulants Type of study: Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Postgrad Med Year: 2021 Document Type: Article Affiliation country: 00325481.2021.1974212

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Thromboembolism / Thrombosis / Blood Coagulation Disorders / Practice Guidelines as Topic / COVID-19 / Anticoagulants Type of study: Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Postgrad Med Year: 2021 Document Type: Article Affiliation country: 00325481.2021.1974212