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Estimation of levels of TNF α, INF α related with serum levels of ferritin and D-dimer the prognosis of SARS CoV 2 infection
Iranian Journal of Ichthyology ; 8(Special Issue 1):78-87, 2021.
Article in English | Scopus | ID: covidwho-1390983
ABSTRACT
Tumor necrosis factor (TNF) and interferon gamma (IFN-γ) are pro-inflammatory and anti-inflammatory cytokine that is central to the development of autoimmune disease, cancer, and protection against infectious pathogens. A case-control study was conducted in the AL HUSSAIN Teaching General hospital in Thi-Qar governorate with a total of 190 individuals involved in the current study, 95 of them were infected with SARC COV 2, and 95 were healthy as control group. Serum was collected from each of them to assess the levels of The, TNFα, INFα, ferritin, D-dimer. TNF-α level increased significantly (P<0.05) (67, 50.6 and 15.25Pg/L), IFN-γ level significantly reduced (P<0.05) (21, 17 and 6.2IU/L), serum ferritin was significantly increased (P<0.05) (685.2, 395, and 87ng/ml). At the last one D dimer (1.7, 0.9 and 0.05mg/L) in the both patient groups (infected and non-infected) and healthy persons. The mean of TNFα, INFα concentration were higher in patients than control group (P<0.05). © 2021 Iranian Society of Ichthyology.
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Collection: Databases of international organizations Database: Scopus Type of study: Prognostic study Language: English Journal: Iranian Journal of Ichthyology Year: 2021 Document Type: Article

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Collection: Databases of international organizations Database: Scopus Type of study: Prognostic study Language: English Journal: Iranian Journal of Ichthyology Year: 2021 Document Type: Article