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Changes of psychotic-like experiences and their association with anxiety/depression among young adolescents before COVID-19 and after the lockdown in China.
Wu, Zhipeng; Liu, Zhening; Zou, Zhulin; Wang, Feiwen; Zhu, Mengran; Zhang, Wen; Tao, Haojuan; Ross, Brendan; Long, Yicheng.
  • Wu Z; Department of Psychiatry, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; China National Clinical Research Center on Mental Disorders, Changsha, Hunan, China.
  • Liu Z; Department of Psychiatry, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; China National Clinical Research Center on Mental Disorders, Changsha, Hunan, China.
  • Zou Z; The High School Attached to Hunan Normal University and Bocai Experimental School, Changsha, Hunan, China.
  • Wang F; Department of Psychiatry, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; China National Clinical Research Center on Mental Disorders, Changsha, Hunan, China.
  • Zhu M; Department of Psychiatry, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; China National Clinical Research Center on Mental Disorders, Changsha, Hunan, China; The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders Be
  • Zhang W; Department of Psychiatry, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; China National Clinical Research Center on Mental Disorders, Changsha, Hunan, China.
  • Tao H; Department of Psychiatry, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; China National Clinical Research Center on Mental Disorders, Changsha, Hunan, China.
  • Ross B; Faculty of Medicine, McGill University, Montreal, Quebec, Canada.
  • Long Y; Department of Psychiatry, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China; China National Clinical Research Center on Mental Disorders, Changsha, Hunan, China. Electronic address: yichenglong@csu.edu.cn.
Schizophr Res ; 237: 40-46, 2021 11.
Article in English | MEDLINE | ID: covidwho-1392548
ABSTRACT

OBJECTIVE:

Lockdown policies during COVID-19 pandemic have potential adverse psychological impacts on youth. However, little is known about their influence on the changes of psychotic-like experiences (PLEs) among adolescents, nor about the possible association between changes in PLEs and changes in anxiety/depression symptoms. We investigated these two questions through a longitudinal comparative study.

METHODS:

In total, 1825 adolescents were surveyed before COVID-19 and after the lockdown in China (T0, October 20th, 2019 and T1, May 18th, 2020). PLEs, anxiety, and depression were measured with paranoia, anxiety and depression subscales of the Mental Health Inventory of Middle school students (MMHI-60). Within-subjects Wilcoxon test, Spearman correlation test, and Kruskal-Wallis test were adopted.

RESULTS:

Significant increase in adolescent PLEs scores was observed after the lockdown (Wilcoxon's w = 9.302, p < 0.001). We also found positive correlation between changes of PLEs and changes of anxiety/depression (Spearman's rho = 0.59/0.53, both p < 0.001). Furthermore, four PLEs trajectories were identified based on the report of PLEs at two timepoints 60.4% with no PLEs, 9.3% remitted PLEs, 16.7% new PLEs, and 13.6% persistent PLEs. Significant difference was found in changes of anxiety/depression among four groups (p < 0.001); notably, the group with new-onset PLEs had the greatest exacerbation in anxiety/depression symptoms (both p Bonferroni <0.001).

CONCLUSIONS:

This work is the first to identify increases in adolescent PLEs across the COVID-19 pandemic and suggested a close longitudinal association between PLEs and anxiety/depression. Our findings have implications for adolescent mental health crisis interventions during the pandemic.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Psychotic Disorders / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Qualitative research / Randomized controlled trials Topics: Long Covid Limits: Adolescent / Humans Language: English Journal: Schizophr Res Journal subject: Psychiatry Year: 2021 Document Type: Article Affiliation country: J.schres.2021.08.020

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Psychotic Disorders / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Qualitative research / Randomized controlled trials Topics: Long Covid Limits: Adolescent / Humans Language: English Journal: Schizophr Res Journal subject: Psychiatry Year: 2021 Document Type: Article Affiliation country: J.schres.2021.08.020