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Impact of COVID-19 on Patients Supported with a Left Ventricular Assist Device.
Zakrzewski, Jack; Coyle, Laura; Aicher, Tracy; Chickerillo, Krystina; Gallagher, Colleen; Kuper, Katelyn; Sciamanna, Chris; Chau, Vinh Q; Tatooles, Antone.
  • Zakrzewski J; From the Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
  • Coyle L; Advocate Heart Institute, Advocate Christ Medical Center, Oak Lawn, Illinois.
  • Aicher T; Advocate Heart Institute, Advocate Christ Medical Center, Oak Lawn, Illinois.
  • Chickerillo K; Advocate Heart Institute, Advocate Christ Medical Center, Oak Lawn, Illinois.
  • Gallagher C; Advocate Heart Institute, Advocate Christ Medical Center, Oak Lawn, Illinois.
  • Kuper K; Advocate Heart Institute, Advocate Christ Medical Center, Oak Lawn, Illinois.
  • Sciamanna C; Advocate Heart Institute, Advocate Christ Medical Center, Oak Lawn, Illinois.
  • Chau VQ; Advocate Heart Institute, Advocate Christ Medical Center, Oak Lawn, Illinois.
  • Tatooles A; Advocate Heart Institute, Advocate Christ Medical Center, Oak Lawn, Illinois.
ASAIO J ; 67(11): 1189-1195, 2021 11 01.
Article in English | MEDLINE | ID: covidwho-1393494
ABSTRACT
Patients on left ventricular assist device (LVAD) support may be susceptible to severe disease and complications from coronavirus disease-19 (COVID-19). The purpose of this study was to describe the clinical course of COVID-19 in LVAD patients. A retrospective review was performed at our center; 28 LVAD patients who developed COVID-19 between March 2020 and March 2021, and six patients with a prior COVID-19 infection who underwent LVAD implantation, were identified and examined. Of the 28 patients, nine (32%) died during the study period, five (18%) during their index hospitalization for COVID-19. Two patients (7%) presented with suspected pump thrombosis. In a nonadjusted binary regression logistic analysis, admission to the intensive care unit (unadjusted odds ratio, 7.6 [CI, 1.2-48], P = 0.03), and the need for mechanical ventilation (unadjusted odds ratio 14 [CI, 1.3-159], P = 0.03) were associated with mortality. The six patients who previously had COVID-19 and subsequently received a LVAD were on intra-aortic balloon pump and inotropic support at time of surgery. All six experienced a complicated and prolonged postoperative course. Three patients (50%) suffered from ischemic stroke, and there was one (17%) 30 day mortality. We observed an increased risk of morbidity and mortality in LVAD patients with COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Heart-Assist Devices / COVID-19 / Heart Failure Type of study: Experimental Studies / Observational study / Prognostic study Limits: Humans Language: English Journal: ASAIO J Journal subject: Transplantation Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Heart-Assist Devices / COVID-19 / Heart Failure Type of study: Experimental Studies / Observational study / Prognostic study Limits: Humans Language: English Journal: ASAIO J Journal subject: Transplantation Year: 2021 Document Type: Article