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COVID-19, cardiovascular diseases and cardiac troponins.
Kim, Chan W; Aronow, Wilbert S.
  • Kim CW; Cardiology Department, & The Department of Medicine, Westchester Medical Center & New York Medical College, Valhalla, NY 10595, USA.
  • Aronow WS; Cardiology Department, & The Department of Medicine, Westchester Medical Center & New York Medical College, Valhalla, NY 10595, USA.
Future Cardiol ; 18(2): 135-142, 2022 02.
Article in English | MEDLINE | ID: covidwho-1394693
ABSTRACT
There has been strong evidence of myocardial injury in COVID-19 patients with significantly elevated serum cardiac troponin (cTn). While the exact mechanism of injury is unclear, possible suggested pathological mechanisms of injury are discussed. These include increased susceptibility of the myocardium and endothelium to viral invasion, underlying hyperinflammatory state and subsequent cytokine storm, a hypercoagulable and prothrombotic state, and indirect myocardial injury due to hypoxemia. As a result of these pathological mechanisms in COVID-19 patients, cTn may be elevated largely due to myocarditis, microangiopathy or myocardial infarction. The utility of cTn as a biomarker for measuring myocardial injury in these patients and assessing its ability as a prognostic factor for clinical outcome is also discussed.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Troponin / Cardiovascular Diseases / COVID-19 / Myocardial Infarction Type of study: Diagnostic study / Prognostic study Limits: Humans Language: English Journal: Future Cardiol Journal subject: Cardiology Year: 2022 Document Type: Article Affiliation country: Fca-2021-0054

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Troponin / Cardiovascular Diseases / COVID-19 / Myocardial Infarction Type of study: Diagnostic study / Prognostic study Limits: Humans Language: English Journal: Future Cardiol Journal subject: Cardiology Year: 2022 Document Type: Article Affiliation country: Fca-2021-0054