COVID-19, cardiovascular diseases and cardiac troponins.
Future Cardiol
; 18(2): 135-142, 2022 02.
Article
in English
| MEDLINE | ID: covidwho-1394693
ABSTRACT
There has been strong evidence of myocardial injury in COVID-19 patients with significantly elevated serum cardiac troponin (cTn). While the exact mechanism of injury is unclear, possible suggested pathological mechanisms of injury are discussed. These include increased susceptibility of the myocardium and endothelium to viral invasion, underlying hyperinflammatory state and subsequent cytokine storm, a hypercoagulable and prothrombotic state, and indirect myocardial injury due to hypoxemia. As a result of these pathological mechanisms in COVID-19 patients, cTn may be elevated largely due to myocarditis, microangiopathy or myocardial infarction. The utility of cTn as a biomarker for measuring myocardial injury in these patients and assessing its ability as a prognostic factor for clinical outcome is also discussed.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Troponin
/
Cardiovascular Diseases
/
COVID-19
/
Myocardial Infarction
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Future Cardiol
Journal subject:
Cardiology
Year:
2022
Document Type:
Article
Affiliation country:
Fca-2021-0054
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