[Correction of mitochondrial dysfunction in the complex rehabilitation of COVID-19]. / Korrektsiya mitokhondrial'noi disfunktsii v kompleksnoi reabilitatsii patsientov, perenesshikh COVID-19.
Zh Nevrol Psikhiatr Im S S Korsakova
; 121(8): 25-29, 2021.
Article
in Russian
| MEDLINE | ID: covidwho-1395468
ABSTRACT
OBJECTIVE:
To study the effectiveness of a course of intravenous administration of cytoflavin in combination with a standard rehabilitation program for post-COVID fatigue syndrome caused by mitochondrial dysfunction. MATERIAL ANDMETHODS:
The dynamic examination of 45 patients with post-COVID syndrome at the second stage of rehabilitation was carried out. The patients were subdivided into 2 groups comparable in gender and age. The volume of lung damage in patients of both groups was also comparable at range of 25-80%. Twenty-four patients of the control group were treated with the standard post-COVID rehabilitation protocol pulse magnetic therapy, inhalation therapy, aeroion therapy, infrared laser therapy, course aerobic training, psychotherapy, and standard drug therapy. Twenty-one patients of the main group additionally received intravenous administration of cytoflavin daily for 10 days. The dynamics of the scores on the Rehabilitation Routing Scale, HDRS, the Asthenic Status Scale, and the 6-minute walk test was analyzed. RESULTS ANDCONCLUSION:
The additional intravenous administration of cytoflavin at the complex rehabilitation of post-COVID syndrome can significantly improve the therapeuticresults:
it significantly improves the overall functional state, reduces depression and fatigue level and increases tolerance to physical exertion.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Fatigue
/
COVID-19
/
Mitochondria
Type of study:
Experimental Studies
/
Prognostic study
/
Randomized controlled trials
Topics:
Long Covid
Limits:
Humans
Language:
Russian
Journal:
Zh Nevrol Psikhiatr Im S S Korsakova
Journal subject:
Neurology
/
Psychiatry
Year:
2021
Document Type:
Article
Affiliation country:
Jnevro202112108125
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