Osteosarcopenia, the co-existence of osteoporosis and sarcopenia, is associated with social frailty in older adults.
Aging Clin Exp Res
; 34(3): 535-543, 2022 Mar.
Article
in English
| MEDLINE | ID: covidwho-1397081
ABSTRACT
BACKGROUND:
Osteosarcopenia is a newly described, aging-associated condition. Social frailty is an important condition whose prevalence may have risen by physical distancing during the coronavirus disease 2019 pandemic. However, the relationship between these two remains unclear.AIMS:
To examine the association between osteosarcopenia and social frailty.METHODS:
This cross-sectional study was conducted using data from outpatients visiting general geriatric hospital frailty clinics. Bone mineral density (BMD) and muscle mass were measured using dual X-ray absorptiometry. Osteoporosis was defined as a BMD of < 70% of the young adult mean, according to the Japan Osteoporosis Society. Sarcopenia was diagnosed as per the Asian Working Group for Sarcopenia 2019 recommendation. Osteosarcopenia was defined as the co-existence of osteoporosis and sarcopenia. We defined social frailty using a questionnaire comprising four items general resources, social resources, social behavior, and basic social needs. Ordinal logistic regression analysis was performed with social frailty status and osteosarcopenia as the dependent and independent variables, respectively.RESULTS:
We included 495 patients (mean age = 76.5 ± 7.2 years) in the analysis; of these, 58.2% were robust and 17.2%, 13.5%, and 11.1% had osteoporosis alone, sarcopenia alone, and osteosarcopenia, respectively. Social frailty prevalence increased stepwise from 8.0% in robust patients to 11.8%, 17.9%, and 29.1% among those with osteoporosis alone, sarcopenia alone, and osteosarcopenia, respectively (P < 0.001). Logistic regression analysis revealed that only osteosarcopenia was significantly associated with social frailty (pooled odds ratio 2.117; 95% confidence interval 1.104-4.213).DISCUSSION:
Comprehensive assessment of osteosarcopenia and social frailty is needed for disability prevention in older adults.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Osteoporosis
/
Sarcopenia
/
Frailty
/
COVID-19
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Topics:
Long Covid
Limits:
Aged
/
Humans
Language:
English
Journal:
Aging Clin Exp Res
Journal subject:
Geriatrics
Year:
2022
Document Type:
Article
Affiliation country:
S40520-021-01968-y
Similar
MEDLINE
...
LILACS
LIS