Understanding the Role of Blood Vessels in the Neurologic Manifestations of Coronavirus Disease 2019 (COVID-19).
Am J Pathol
; 191(11): 1946-1954, 2021 11.
Article
in English
| MEDLINE | ID: covidwho-1397147
ABSTRACT
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was originally identified as an outbreak in Wuhan, China, toward the end of 2019 and quickly became a global pandemic, with a large death toll. Originally identified as a respiratory disease, similar to previously discovered SARS and Middle East respiratory syndrome (MERS), concern has since been raised about the effects of SARS-CoV-2 infection on the vasculature. This viral-vascular involvement is of particular concern with regards to the small vessels present in the brain, with mounting evidence demonstrating that SARS-CoV-2 is capable of crossing the blood-brain barrier. Severe symptoms, termed coronavirus disease 2019 (COVID-19), often result in neurologic complications, regardless of patient age. These neurologic complications range from mild to severe across all demographics; however, the long-term repercussions of neurologic involvement on patient health are still unknown.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Blood Vessels
/
Blood-Brain Barrier
/
COVID-19
/
Nervous System Diseases
Topics:
Long Covid
Limits:
Humans
Language:
English
Journal:
Am J Pathol
Year:
2021
Document Type:
Article
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