Your browser doesn't support javascript.
Neurocognitive Outcome Following Recovery from Severe Acute Respiratory Syndrome - Coronavirus-1 (SARS-CoV-1).
Pinnock, Farena S; Rich, Jill B; Vasquez, Brandon; Wiegand, Melanie; Patcai, John; Troyer, Angela K; Murphy, Kelly J.
  • Pinnock FS; Neuropsychology & Cognitive Health, Baycrest Health Sciences, Toronto, ON, Canada.
  • Rich JB; Neuropsychology & Cognitive Health, Baycrest Health Sciences, Toronto, ON, Canada.
  • Vasquez B; Department of Psychology, York University, Toronto, ON, Canada.
  • Wiegand M; Neuropsychology & Cognitive Health, Baycrest Health Sciences, Toronto, ON, Canada.
  • Patcai J; Department of Occupational Science & Occupational Therapy, University of Toronto, Toronto, ON, Canada.
  • Troyer AK; Department of Psychology, York University, Toronto, ON, Canada.
  • Murphy KJ; Department of Medicine, University of Toronto, Toronto, ON, Canada.
J Int Neuropsychol Soc ; 28(9): 891-901, 2022 10.
Article in English | MEDLINE | ID: covidwho-1397820
ABSTRACT

OBJECTIVE:

Severe acute respiratory syndrome (SARS) is a highly contagious viral respiratory illness associated with hypoxia and dyspnea. Many of those who contracted and recovered from SARS during the 2002-2003 outbreak reported persistent physical, psychological, and cognitive difficulties. Here, we investigated the residual influences of SARS on cognition for a subset of healthcare professionals who recovered and were referred for neuropsychological evaluation through their workplace insurance.

METHOD:

Twenty-eight healthcare professionals were evaluated on neuropsychological and mood functioning approximately 1.5 years post-recovery from a severe respiratory illness. Test scores were compared with age-matched normative data, and correlations were examined between mood, self-report memory scales, subjective complaints (e.g., poor concentration, pain, fatigue), illness severity (i.e., length of hospitalization, oxygen use during hospital stay), and cognitive performance.

RESULTS:

Participants performed within age expectations on the majority of cognitive measures including overall memory ability. Although processing speed was generally within normal limits, 43% showed significant speed-accuracy trade-offs favoring accuracy over maintaining speed. Deficits were observed on measures of complex attention, such as working memory and the ability to sustain attention under conditions of distraction. Participants endorsed poorer memory ability than same-age peers on a meta-memory measure and mild to moderate depression and anxiety symptoms. Objective test performance was largely uncorrelated with self-reports, mood, or illness severity, except for moderate correlations between complex attention and participants' subjective ratings of Everyday Task-Oriented Memory.

CONCLUSIONS:

These findings demonstrate specific long-term cognitive deficits associated with SARS and provide further evidence of the cognitive effects of hypoxic illnesses.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Cognition Disorders / Severe Acute Respiratory Syndrome / Severe acute respiratory syndrome-related coronavirus Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: J Int Neuropsychol Soc Journal subject: Neurology / Psychology Year: 2022 Document Type: Article Affiliation country: S1355617721001107

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Cognition Disorders / Severe Acute Respiratory Syndrome / Severe acute respiratory syndrome-related coronavirus Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: J Int Neuropsychol Soc Journal subject: Neurology / Psychology Year: 2022 Document Type: Article Affiliation country: S1355617721001107