Tilorone, a Broad-Spectrum Antiviral for Emerging Viruses.
Antimicrob Agents Chemother
; 64(5)2020 04 21.
Article
in English
| MEDLINE | ID: covidwho-13986
ABSTRACT
Tilorone is a 50-year-old synthetic small-molecule compound with antiviral activity that is proposed to induce interferon after oral administration. This drug is used as a broad-spectrum antiviral in several countries of the Russian Federation. We have recently described activity in vitro and in vivo against the Ebola virus. After a broad screening of additional viruses, we now describe in vitro activity against Chikungunya virus (CHIK) and Middle Eastern respiratory syndrome coronavirus (MERS-CoV).
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Antiviral Agents
/
Tilorone
/
Chikungunya virus
/
Coronavirus
/
Communicable Diseases, Emerging
/
Ebolavirus
/
Middle East Respiratory Syndrome Coronavirus
Limits:
Humans
Language:
English
Year:
2020
Document Type:
Article
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