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Sars-CoV2 vaccine hesitancy in Italy: A survey on subjects with diabetes.
Scoccimarro, Daniele; Panichi, Lorenzo; Ragghianti, Benedetta; Silverii, Antonio; Mannucci, Edoardo; Monami, Matteo.
  • Scoccimarro D; University of Florence, Florence, Italy.
  • Panichi L; University of Florence, Florence, Italy.
  • Ragghianti B; Diabetology Unit, Careggi Hospital, Florence, Italy.
  • Silverii A; University of Florence, Florence, Italy.
  • Mannucci E; University of Florence, Florence, Italy.
  • Monami M; Diabetology Unit, Careggi Hospital, Florence, Italy. Electronic address: matteo.monami@unifi.it.
Nutr Metab Cardiovasc Dis ; 31(11): 3243-3246, 2021 10 28.
Article in English | MEDLINE | ID: covidwho-1401752
ABSTRACT
BACKGROUND AND

AIMS:

Vaccine Hesitancy (VH) is a relevant obstacle for the COVID-19 vaccination campaign. The aim of this study is to assess the proportion of subjects unwilling to vaccinate among patients with type 1 (T1DM) and 2 (T2DM) diabetes, exploring factors associated with VH. METHODS AND

RESULTS:

A purposely created interview was delivered from physicians to a consecutive series of adult (>18 years) subjects with diabetes referring to the Diabetes Outpatient Clinic of Careggi Hospital, Florence, from January 1st to April 30th 2021. Out of 502 subjects enrolled, 92 were vaccine hesitant respondents (18.3%); the corresponding figure for T1DM and T2DM was 13.0% (N = 14), and 19.9% (N = 78), respectively. After adjusting for age, higher HbA1c (1.07 [1.02-1.13], p = 0.008) and triglycerides levels (1.03 [1.01-1.06], p = 0.011) were positively associated with VH, among patients with T1DM. At multivariate analysis, after adjusting for age, creatinine, and statin use, patients with T2DM affected by obesity (9.98 [4.89-9.59], p < 0.01) and with lower levels of creatinine (0.36 [0.21-0.54], p = 0.029) were more likely to refuse COVID vaccination.

CONCLUSIONS:

Hesitancy toward COVID-19 vaccination among subjects with diabetes is not negligible and seems to be more prevalent in individuals with lower adherence to medical prescriptions and/or reduced concerns over their health. This suggests the need for specific interventions to increase awareness and counter prejudices on vaccines.
Subject(s)
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccination / Diabetes Mellitus, Type 1 / Diabetes Mellitus, Type 2 / COVID-19 Vaccines / COVID-19 Type of study: Observational study / Qualitative research / Randomized controlled trials Topics: Vaccines Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Nutr Metab Cardiovasc Dis Journal subject: Vascular Diseases / Cardiology / Nutritional Sciences / Metabolism Year: 2021 Document Type: Article Affiliation country: J.numecd.2021.09.002

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccination / Diabetes Mellitus, Type 1 / Diabetes Mellitus, Type 2 / COVID-19 Vaccines / COVID-19 Type of study: Observational study / Qualitative research / Randomized controlled trials Topics: Vaccines Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Nutr Metab Cardiovasc Dis Journal subject: Vascular Diseases / Cardiology / Nutritional Sciences / Metabolism Year: 2021 Document Type: Article Affiliation country: J.numecd.2021.09.002