Vogt-Koyanagi-Harada Disease Associated with COVID-19 mRNA Vaccine.

Koong, Lin Ru; Chee, Wai Kitt; Toh, Zhi Hong; Ng, Xin Le; Agrawal, Rupesh; Ho, Su Ling

Koong, Lin Ru; Chee, Wai Kitt; Toh, Zhi Hong; Ng, Xin Le; Agrawal, Rupesh; Ho, Su Ling.

Koong LR; National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.
Chee WK; National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.
Toh ZH; National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.
Ng XL; National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.
Agrawal R; National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.
Ho SL; Lee Kong Chian School of Medicine, Singapore.

Ocul Immunol Inflamm ; 29(6): 1212-1215, 2021 Aug 18.

Article in English | MEDLINE | ID: covidwho-1402198

ABSTRACT

ABSTRACT

A 54-year-old Chinese male with no previous ocular history presented to the ophthalmology department for the bilateral acute painless blurring of vision after receiving the 1st dose of COVID-19 mRNA vaccine (PFIZER-BioNTech/COMIRNATY). Clinical examination and imaging tests were consistent with Vogt-Koyanagi-Hara disease. The patient responded well with a high dose of intravenous methylprednisolone followed by a tapering dose of oral prednisolone.

Subject(s)

BNT162 Vaccine/adverse effects; COVID-19/prevention & control; SARS-CoV-2; Uveomeningoencephalitic Syndrome/etiology; Vaccination/adverse effects; Autoimmunity; Fluorescein Angiography; Glucocorticoids/therapeutic use; Humans; Male; Methylprednisolone/therapeutic use; Middle Aged; Pulse Therapy, Drug; Tomography, Optical Coherence; Uveomeningoencephalitic Syndrome/diagnosis; Uveomeningoencephalitic Syndrome/drug therapy

Keywords

COVID-19 vaccine; PfizerBioNtech; VKH disease; exudative retinal detachment; vaccine side effects

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Uveomeningoencephalitic Syndrome / Vaccination / SARS-CoV-2 / COVID-19 / BNT162 Vaccine Type of study: Case report / Diagnostic study / Prognostic study Topics: Vaccines Limits: Humans / Male / Middle aged Language: English Journal: Ocul Immunol Inflamm Journal subject: Allergy and Immunology / Ophthalmology Year: 2021 Document Type: Article Affiliation country: 09273948.2021.1974492

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