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Pseudotumor Cerebri Syndrome as a Neurologic Involvement of Multisystem Inflammatory Syndrome in Children: A Case Report.
Sofuoglu, Ayse Irem; Akçay, Nihal; Sevketoglu, Esra; Bektas, Gonca.
  • Sofuoglu AI; Division of Pediatric Intensive Care, Department of Pediatrics, Bakirkoy Dr. Sadi Konuk Research and Training Hospital, Istanbul, Turkey.
  • Akçay N; Division of Pediatric Intensive Care, Department of Pediatrics, Bakirkoy Dr. Sadi Konuk Research and Training Hospital, Istanbul, Turkey.
  • Sevketoglu E; Division of Pediatric Intensive Care, Department of Pediatrics, Bakirkoy Dr. Sadi Konuk Research and Training Hospital, Istanbul, Turkey.
  • Bektas G; Division of Pediatric Neurology, Department of Pediatrics, Bakikoy Dr. Sadi Konuk Research and Training Hospital, Istanbul, Turkey.
J Trop Pediatr ; 67(4)2021 08 27.
Article in English | MEDLINE | ID: covidwho-1402692
ABSTRACT

BACKGROUND:

Coronavirus disease 2019 may have neurological manifestations including meningitis, encephalitis, post-infectious brainstem encephalitis and Guillain-Barre syndrome. Neuroinflammation has been claimed as a possible cause. Here, we present a child with multisystem inflammatory syndrome in children (MIS-C) who developed pseudotumor cerebri syndrome (PTCS) during the disease course. CASE A 11-year-old girl presented with 5 days of fever, headache and developed disturbance of consciousness, respiratory distress, conjunctivitis and diffuse rash on her trunk. Immunoglobulin M and G antibodies against severe acute respiratory syndrome coronavirus 2 were positive in her serum. She was diagnosed with MIS-C. On day 10, she developed headache and diplopia. Left abducens paralysis and bilateral grade 3 papilledema were observed. Brain magnetic resonance imaging revealed optic nerve head protrusion, globe flattening. She was diagnosed with secondary PTCS. Papilledema and abducens paralysis improved under acetazolamide and topiramate. Neurological examination became normal after 2 months.

CONCLUSION:

PTCS may emerge related to MIS-C.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pseudotumor Cerebri / COVID-19 Type of study: Case report / Diagnostic study / Prognostic study Limits: Child / Female / Humans Language: English Year: 2021 Document Type: Article Affiliation country: Tropej

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pseudotumor Cerebri / COVID-19 Type of study: Case report / Diagnostic study / Prognostic study Limits: Child / Female / Humans Language: English Year: 2021 Document Type: Article Affiliation country: Tropej