Your browser doesn't support javascript.
In vitro efficacy of Artemisia extracts against SARS-CoV-2.
Nie, Chuanxiong; Trimpert, Jakob; Moon, Sooyeon; Haag, Rainer; Gilmore, Kerry; Kaufer, Benedikt B; Seeberger, Peter H.
  • Nie C; Institute for Virology, Freie Universität Berlin, Robert von Ostertag-Str. 7-13, 14163, Berlin, Germany.
  • Trimpert J; Department of Chemistry and Biochemistry, Freie Universität Berlin, Takustrasse 3, 14195, Berlin, Germany.
  • Moon S; Institute for Virology, Freie Universität Berlin, Robert von Ostertag-Str. 7-13, 14163, Berlin, Germany.
  • Haag R; Department for Biomolecular Systems, Max-Planck Institute for Colloids and Interfaces, Am Mühlenberg 1, 14476, Potsdam, Germany.
  • Gilmore K; Department of Chemistry and Biochemistry, Freie Universität Berlin, Takustrasse 3, 14195, Berlin, Germany.
  • Kaufer BB; Department for Biomolecular Systems, Max-Planck Institute for Colloids and Interfaces, Am Mühlenberg 1, 14476, Potsdam, Germany.
  • Seeberger PH; Department of Chemistry, University of Connecticut, 55 N. Eagleville Rd., Storrs, CT, 06268, USA.
Virol J ; 18(1): 182, 2021 09 08.
Article in English | MEDLINE | ID: covidwho-1403244
Preprint
This scientific journal article is probably based on a previously available preprint. It has been identified through a machine matching algorithm, human confirmation is still pending.
See preprint
ABSTRACT

BACKGROUND:

Traditional medicines based on herbal extracts have been proposed as affordable treatments for patients suffering from coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Teas and drinks containing extracts of Artemisia annua and Artemisia afra have been widely used in Africa in efforts to prevent SARS-CoV-2 infection and fight COVID-19.

METHODS:

The plant extracts and Covid-Organics drink produced in Madagascar were tested for plaque reduction using both feline coronavirus and SARS-CoV-2 in vitro. Their cytotoxicities were also investigated.

RESULTS:

Several extracts as well as Covid-Organics inhibited SARS-CoV-2 and FCoV infection at concentrations that did not affect cell viability.

CONCLUSIONS:

Some plant extracts show inhibitory activity against FCoV and SARS-CoV-2. However, it remains unclear whether peak plasma concentrations in humans can reach levels needed to inhibit viral infection following consumption of teas or Covid-Organics. Clinical studies are required to evaluate the utility of these drinks for COVID-19 prevention or treatment of patients.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Plant Extracts / Artemisia / SARS-CoV-2 Type of study: Experimental Studies / Prognostic study Topics: Traditional medicine Limits: Animals Language: English Journal: Virol J Journal subject: Virology Year: 2021 Document Type: Article Affiliation country: S12985-021-01651-8

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Plant Extracts / Artemisia / SARS-CoV-2 Type of study: Experimental Studies / Prognostic study Topics: Traditional medicine Limits: Animals Language: English Journal: Virol J Journal subject: Virology Year: 2021 Document Type: Article Affiliation country: S12985-021-01651-8