Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy.

Baj, Andreina; Novazzi, Federica; Pasciuta, Renee; Genoni, Angelo; Ferrante, Francesca Drago; Valli, Marilena; Partenope, Michele; Tripiciano, Rosalia; Ciserchia, Andrea; Catanoso, Giuseppe; Focosi, Daniele; Maggi, Fabrizio

Baj, Andreina; Novazzi, Federica; Pasciuta, Renee; Genoni, Angelo; Ferrante, Francesca Drago; Valli, Marilena; Partenope, Michele; Tripiciano, Rosalia; Ciserchia, Andrea; Catanoso, Giuseppe; Focosi, Daniele; Maggi, Fabrizio.

Emerg Infect Dis ; 27(12): 3180-3182, 2021 Dec.

Article in English | MEDLINE | ID: covidwho-1403446

ABSTRACT

ABSTRACT

The Delta variant of concern of severe acute respiratory syndrome coronavirus 2 is dominant worldwide. We report a case cluster caused by Delta sublineage B.1.617.2 harboring the mutation E484K in Italy during July 11-July 29, 2021. This mutation appears to affect immune response and vaccine efficacy; monitoring its appearance is urgent.

Subject(s)

COVID-19; SARS-CoV-2; Humans; Italy/epidemiology; Mutation

Keywords

B.1.617.2; COVID-19; E484K; Italy; SARS-CoV-2; coronavirus disease; delta variant; mutation of concern; respiratory infections; severe acute respiratory syndrome coronavirus 2; variant of concern; viruses; zoonoses

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Observational study Topics: Vaccines / Variants Limits: Humans Country/Region as subject: Europa Language: English Journal: Emerg Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article

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