[Practical guidance for the management of patients with hematological disorders during the coronavirus disease 2019 pandemic in Japan].
Rinsho Ketsueki
; 62(8): 1178-1185, 2021.
Article
in Japanese
| MEDLINE | ID: covidwho-1404086
ABSTRACT
During the nosocomial coronavirus disease 2019 (COVID-19) outbreak, patients with hematological disorders showed poorer survival and aggressive course of respiratory failure than patients with other disorders. Two patients with immune thrombocytopenia who were being treated with prednisolone experienced severe respiratory failure related to COVID-19 and finally died. Patients who were yet to achieve remission and those receiving chemotherapy with steroids had a higher risk of death, and the mortality rate was higher in patients with lymphoid malignancies, including lymphoma and myeloma, than in those with myeloid malignancies. We describe the case of a myeloma patient in whom high-dose steroid administration was able to achieve considerable resolution of respiratory failure. In patients with unsuccessful seroconversion of anti-SARS-CoV-2 IgG antibodies, recurrence or re-infection of COVID-19 should be closely monitored.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pandemics
/
COVID-19
Type of study:
Case report
/
Observational study
/
Prognostic study
Limits:
Humans
Country/Region as subject:
Asia
Language:
Japanese
Journal:
Rinsho Ketsueki
Year:
2021
Document Type:
Article
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