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Two Patients With Severe COVID Pneumonia Treated With the Seraph-100 Microbind Affinity Blood Filter.
Kelly, Mark M; Wilkinson, Jared D; Rastegar, Mandana; Lewis, Michael S; Betancourt, Jaime.
  • Kelly MM; 8783UCLA, Los Angeles, CA, USA.
  • Wilkinson JD; 19975VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA.
  • Rastegar M; David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
  • Lewis MS; 8783UCLA, Los Angeles, CA, USA.
  • Betancourt J; 19975VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA.
J Intensive Care Med ; 36(10): 1228-1232, 2021 Oct.
Article in English | MEDLINE | ID: covidwho-1405275
ABSTRACT
We present 2 patients with rapidly escalating oxygen requirements from severe acute respiratory syndrome coronavirus 2 infection (COVID-19) treated with the Seraph100 Microbind Affinity Blood Filter under Emergency Use Authorization from the US Federal Drug Administration. The Seraph100 is an extracorporeal hemoperfusion filter previously demonstrated to remove viral particles and pro-inflammatory cytokines from the blood. Treatment with the Seraph100 filter was associated with a rapid improvement in oxygenation and both patients were discharged from the hospital without supplemental oxygen.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia / Hemoperfusion / COVID-19 Type of study: Case report Limits: Humans Language: English Journal: J Intensive Care Med Journal subject: Critical Care Year: 2021 Document Type: Article Affiliation country: 08850666211039744

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia / Hemoperfusion / COVID-19 Type of study: Case report Limits: Humans Language: English Journal: J Intensive Care Med Journal subject: Critical Care Year: 2021 Document Type: Article Affiliation country: 08850666211039744