Multinational Observational Cohort Study of COVID-19-Associated Pulmonary Aspergillosis<sup>1</sup>.

Janssen, Nico A F; Nyga, Rémy; Vanderbeke, Lore; Jacobs, Cato; Ergün, Mehmet; Buil, Jochem B; van Dijk, Karin; Altenburg, Josje; Bouman, Catherine S C; van der Spoel, Hans I; Rijnders, Bart J A; Dunbar, Albert; Schouten, Jeroen A; Lagrou, Katrien; Bourgeois, Marc; Reynders, Marijke; van Regenmortel, Niels; Rutsaert, Lynn; Lormans, Piet; Feys, Simon; Debavaye, Yves; Tamion, Fabienne; Costa, Damien; Maizel, Julien; Dupont, Hervé; Chouaki, Taieb; Nseir, Saad; Sendid, Boualem; Brüggemann, Roger J M; van de Veerdonk, Frank L; Wauters, Joost; Verweij, Paul E

Multinational Observational Cohort Study of COVID-19-Associated Pulmonary Aspergillosis¹.

Janssen, Nico A F; Nyga, Rémy; Vanderbeke, Lore; Jacobs, Cato; Ergün, Mehmet; Buil, Jochem B; van Dijk, Karin; Altenburg, Josje; Bouman, Catherine S C; van der Spoel, Hans I; Rijnders, Bart J A; Dunbar, Albert; Schouten, Jeroen A; Lagrou, Katrien; Bourgeois, Marc; Reynders, Marijke; van Regenmortel, Niels; Rutsaert, Lynn; Lormans, Piet; Feys, Simon; Debavaye, Yves; Tamion, Fabienne; Costa, Damien; Maizel, Julien; Dupont, Hervé; Chouaki, Taieb; Nseir, Saad; Sendid, Boualem; Brüggemann, Roger J M; van de Veerdonk, Frank L; Wauters, Joost; Verweij, Paul E.

Emerg Infect Dis ; 27(11): 2892-2898, 2021 11.

Article in English | MEDLINE | ID: covidwho-1551452

ABSTRACT

ABSTRACT

We performed an observational study to investigate intensive care unit incidence, risk factors, and outcomes of coronavirus disease-associated pulmonary aspergillosis (CAPA). We found 10%-15% CAPA incidence among 823 patients in 2 cohorts. Several factors were independently associated with CAPA in 1 cohort and mortality rates were 43%-52%.

Subject(s)

COVID-19; Invasive Pulmonary Aspergillosis; Pulmonary Aspergillosis; Cohort Studies; Humans; SARS-CoV-2

Keywords

Aspergillus; COVID-19; SARS; SARS-CoV-2; coronavirus; coronavirus disease; epidemiology; fungi; invasive pulmonary aspergillosis; mortality rates; mycology; respiratory infections; risk factors; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pulmonary Aspergillosis / Invasive Pulmonary Aspergillosis / COVID-19 Type of study: Cohort study / Observational study / Prognostic study Limits: Humans Language: English Journal: Emerg Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article

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