Emerging nanomaterials applied for tackling the COVID-19 cytokine storm.
J Mater Chem B
; 9(39): 8185-8201, 2021 10 13.
Article
in English
| MEDLINE | ID: covidwho-1414146
ABSTRACT
During the global outbreak of coronavirus disease 2019 (COVID-19), a hyperinflammatory state called the cytokine storm was recognized as a major contributor to multiple organ failure and mortality. However, to date, the diagnosis and treatment of the cytokine storm remain major challenges for the clinical prognosis of COVID-19. In this review, we outline various nanomaterial-based strategies for preventing the COVID-19 cytokine storm. We highlight the contribution of nanomaterials to directly inhibit cytokine release. We then discuss how nanomaterials can be used to deliver anti-inflammatory drugs to calm the cytokine storm. Nanomaterials also play crucial roles in diagnostics. Nanomaterial-based biosensors with improved sensitivity and specificity can be used to detect cytokines. In summary, emerging nanomaterials offer platforms and tools for the detection and treatment of the COVID-19 cytokine storm and future pandemic.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Nanostructures
/
Cytokine Release Syndrome
/
COVID-19
/
COVID-19 Drug Treatment
Type of study:
Diagnostic study
/
Prognostic study
Topics:
Long Covid
Limits:
Animals
/
Humans
Language:
English
Journal:
J Mater Chem B
Year:
2021
Document Type:
Article
Affiliation country:
D1tb01446c
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